Role of parathormone and altered calcium homeostasis in bone disease in Egyptian adult patients with thalassemia /

Salwa Hassan Ahmed Ali

Role of parathormone and altered calcium homeostasis in bone disease in Egyptian adult patients with thalassemia / دراسة دور هرمون الغدة الجاردرقية و خلل نسبة الكالسيوم بالجسم على العظام فى مرضى الثلاسيما المصريين البالغين Salwa Hassan Ahmed Ali ; Supervised Alia Abdelaziz Saad , Hala Mahmoud Fahmy , Mohamed Talaat - Cairo : Salwa Hassan Ahmed Ali , 2014 - 162 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Beta Thalassemia is the most common chronic hemolytic anemia in Egypt (85.1%). Iron overload remains the biggest threat to the health of patients with thalassemia. Multi - transfused thalassaemic patients may develop severe endocrine complications due to iron overload. Etiology of bone disease in thalassemic patients is poorly understood. Number of studies has examined the effect of various conditions on the pathogenesis of bone disease including ineffective erythropoiesis, iron overload, vitamin D concentrations, and the influence of endocrinopathies. Hypopara-thyroidism was found in 7.6% of a group of thalassemic patients in Iran but 3.6 7% reported in Italian thalassemic patients



Hypoparathyroidim Iron overload Thalassemia
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