A study of human papilloma virus (HPV) infection of the cervix in Egyptian females by cytology, histopathology, colposcopy and HPV genotyping /

Ahmed Farid Elshazly

A study of human papilloma virus (HPV) infection of the cervix in Egyptian females by cytology, histopathology, colposcopy and HPV genotyping / دراسة الاصابة بفيروس الورم الحليمى البشرى فى عنق الرحم لدى السيدات المصريات عن طريق علم الخلية والهيستوباثولوجى والمنظار المهبلى والنمط الجينى لفيروس الورم الحليمى البشرى Ahmed Farid Elshazly ; Supervised Mona Abdelbadeeh Nayel , Olfat Gamil Shaker , Hala Naguib Hosni - Cairo : Ahmed Farid Elshazly , 2014 - 165 Leaves : facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

In this study the golden standard test for detection of HPV was considered PCR-ISH tissue. We found PCR-ISH tissue was positive in 16 cases (53.33%) and 14 cases (46.6%) were negative. The age of studied group ranged from (20-50) years with mean and standard deviation (SD) 32.77+7.99 while the duration of marriage in 29 cases (0.5-30) years, as one was divorced, with mean and SD 12.95+8.26. Comparing the result of pap smear, histopathology, colposcopy and PCR swap in diagnosis of HPV with the golden standard test ISH PCR tissue, the sensitivity were 87.5%, 100%, 62.5% and 56,2% respectively but the specificity were 78.6%, 42.9%, 28.6% and 100% respectively This study aimed to evaluate the different methods of diagnosis of cervical HPV infection in Egyptian females by cytology, histopathology, colposcopy and HPV genotyping.This study included 30 patient with either abnormal pap smears prior to colposcopic examination (10 cases) and abnormal T Z zone on colposcopic examination (20 cases).We considered Pap smear result suggestive of the presence of HPV infection when we found (ASUS, LSIL, HSIL, koliocytic atypia)



Histopathology HPV PCR
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