Immunohistochemical expression of phosphatidyl-inositol-30 kinase (PI3K)/Akt2 in oral epithelial dysplasia and squamous cell carcinoma /
Mohamed Osama Mostafa
Immunohistochemical expression of phosphatidyl-inositol-30 kinase (PI3K)/Akt2 in oral epithelial dysplasia and squamous cell carcinoma / في الخلايا الطلائية الفموية الشاذة وسرطان الخلايا الحرشفية (PI3K)/Akt2التعبير المناعى للبروتين فوسفاتيديل اينيستول -30 كينيز Mohamed Osama Mostafa ; Supervised Dalia Hussein Elrouby , Hend Mohamed Wagih - Cairo : Mohamed Osama Mostafa , 2014 - 109 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Pathology
Oral cancer is one of the most common cancers worldwide and is thought to arise from progressive dysplastic changes of the oral squamous epithelium. Thirty-six paraffin blocks were investigated in this study including fifteen premalignant dysplastic lesions and fifteen OSCC. In addition, six specimens from normal tissue were used as a control. Slides were immunostained by the monoclonal mouse anti-human Akt2 antibody. The immunostained sections were analyzed by an image analyzer computer system using the software LeciaQwin 500.The area percent of the positive nuclear and cytoplasmic immunoreaction was measured in normal oral tissue, in oral dysplastic lesions and in different grades of SCC
Akt (PKB) Oral cancer Protein kinase B
Immunohistochemical expression of phosphatidyl-inositol-30 kinase (PI3K)/Akt2 in oral epithelial dysplasia and squamous cell carcinoma / في الخلايا الطلائية الفموية الشاذة وسرطان الخلايا الحرشفية (PI3K)/Akt2التعبير المناعى للبروتين فوسفاتيديل اينيستول -30 كينيز Mohamed Osama Mostafa ; Supervised Dalia Hussein Elrouby , Hend Mohamed Wagih - Cairo : Mohamed Osama Mostafa , 2014 - 109 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Pathology
Oral cancer is one of the most common cancers worldwide and is thought to arise from progressive dysplastic changes of the oral squamous epithelium. Thirty-six paraffin blocks were investigated in this study including fifteen premalignant dysplastic lesions and fifteen OSCC. In addition, six specimens from normal tissue were used as a control. Slides were immunostained by the monoclonal mouse anti-human Akt2 antibody. The immunostained sections were analyzed by an image analyzer computer system using the software LeciaQwin 500.The area percent of the positive nuclear and cytoplasmic immunoreaction was measured in normal oral tissue, in oral dysplastic lesions and in different grades of SCC
Akt (PKB) Oral cancer Protein kinase B