Uses of nitriles and carbonyl compounds in the synthesis of biologically active heterocyclic compounds /
Aya Elsayed Elsayed Khedr
Uses of nitriles and carbonyl compounds in the synthesis of biologically active heterocyclic compounds / استخدامات مركبات النيتريل و الكاربونيل لتحضير المركبات غير متجانسة الحلقة ذات النشاط البيولوجى Aya Elsayed Elsayed Khedr ; Supervised Raafat Milad Mohareb - Cairo : Aya Elsayed Elsayed Khedr , 2016 - 139 P. : charts , photographs ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
In this work the reaction of ethylacetoacetate (1) with Ü-naphthylamine (2) gave the N-(Naphthalen-1-yl)-3-oxobutanamid (3). The latter products underwent a series of heterocyclization reactions to yield pyridine, pyran, thiophene and pyrazole derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured
1,3-dicarbonyl compounds Heterocycles Synthesis
Uses of nitriles and carbonyl compounds in the synthesis of biologically active heterocyclic compounds / استخدامات مركبات النيتريل و الكاربونيل لتحضير المركبات غير متجانسة الحلقة ذات النشاط البيولوجى Aya Elsayed Elsayed Khedr ; Supervised Raafat Milad Mohareb - Cairo : Aya Elsayed Elsayed Khedr , 2016 - 139 P. : charts , photographs ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
In this work the reaction of ethylacetoacetate (1) with Ü-naphthylamine (2) gave the N-(Naphthalen-1-yl)-3-oxobutanamid (3). The latter products underwent a series of heterocyclization reactions to yield pyridine, pyran, thiophene and pyrazole derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured
1,3-dicarbonyl compounds Heterocycles Synthesis