Synthesis of biologically active new heterocyclic compounds derived from cyanomethylene, carbonyl and Ý-dicarbonyl compounds /

Ereeny Elkess Mikhael Aziz

Synthesis of biologically active new heterocyclic compounds derived from cyanomethylene, carbonyl and Ý-dicarbonyl compounds / تحضير مركبات جديدة نشطة حيوية غير متجانسة الحلقة المشتقة من مركبات السيانو ميثيلين - الكاربونيل و البيتا ثنائى الكاربونيل Ereeny Elkess Mikhael Aziz ; Supervised Rafat Milad Mohareb , Wafaa Hosney - Cairo : Ereeny Elkess Mikhael Aziz , 2016 - 130 P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry

In this work we synthesized a series of heterocyclic compounds through starting from compound 3. The synthesized compounds including pyrazole, oxazole, pyran, pyridine and pyrimidine derivatives. The structures of the newly synthesized products were confirmed on the basis of their respective analytical and spectral data. The cytotoxicity of the newly synthesized products was measured against three cancer cell lines where some compounds showed high cytotoxicity



Oxazole Pyran Pyrazole
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