Studying the efficacy of fractional CO₂ laser in the treatment of postinflammatory hyperpigmentation /

Yasmine Mohamed Abdelazeem Elhosary

Studying the efficacy of fractional CO₂ laser in the treatment of postinflammatory hyperpigmentation / دراسة كفاءة ليزر ثاني أكسيد الكربون التجزئي في علاج اسمرار ما بعد الالتهاب Yasmine Mohamed Abdelazeem Elhosary ; Supervised Rehab Mohamed Sobhi , Pakinam Ibrahim Nabil Mostafa - Cairo : Yasmine Mohamed Abdelazeem Elhosary , 2018 - 106 P. : charts , fscsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

Background: Postinflammatory hyperpigmentation (PIH) is an acquired hyperpigmentation that involves areas of prior cutaneous inflammation. By fractional CO₂ laser the formation of MENDs (Microscopic Epidermal Necrotic Debris) could improve hyperpigmentation through the transepidermal elimination of the dermal contents including melanin. Objective: The aim of this work is to evaluate the efficacy of fractional CO₂ laser in the treatment of postinflammatory hyperpigmentation. Patients and Methods: Thirty patients of both sexes with postinflammatory hyperpigmentation of skin types 3, 4, 5 were enrolled in this study. Each patient was subjected to 3 sessions of fractional CO₂ laser with 1 month interval and follow up after 1 month and evaluation of the level of pigmentation by woods lamp before starting the first session and after the last session. Clinical evaluation was done by photography, as well as patients satisfaction score, two blinded physician score and a color panel score. Results: In the present study we observed excellent improvement in 8 patients (26.7 %), marked improvement in 12 patients (40%), moderate improvement in 6 patients (20%) and mild improvement in 4 patients (13.3%), with no incidence of side effects. There was no significant relation between the degree of improvement and age, sex, skin type, etiology, or the site of the lesion Fractional CO₂ laser is a safe and effective method in treating postinflammatory hyperpigmentation



Fractional CO₂ laser Laser Postinflammatory hyperpigmentation
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