Comparison between femtosecond assisted keratoplasty and conventional keratoplasty /

Mohamed Youssry Abdelmonaiem

Comparison between femtosecond assisted keratoplasty and conventional keratoplasty / مقارنة بين ترقيع القرنية باستخدام الفيمتو ليزر وترقيع القرنية الثاقب التقليدى Mohamed Youssry Abdelmonaiem ; Supervised Ibrahim Mohy Eldin Taher , Karim Adly Raafat , Amr Abdalrahim Mostafa Aldib - Cairo : Mohamed Youssry Abdelmonaiem , 2020 - 84 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Science - Department of Laser Application in Medical and Biological

Purpose and aim of the work: To compare between femtoseconds laser-assisted keratoplasty (FAK) and penetrating keratoplasty (PK) using microscopic examination (light and transmission electron microscopy) of the cut edges of the remaining donor cornea. Material and Methods: Prospective observational study involving 10 eyes; 5 eyes by femto assisted keratoplasty FAK (top hat technique) and the other 5 eyes by conventional trephination method. Main outcomes are histological findings at the cut edge of the donor corneal graft tissue (at 3, 6, 9, and 12 oclock). Results: In femto assisted trephined corneas (FAK), cellular and ultra-cellular changes in the form of marked edema, disruption and disorganization of the collagen fibers, and nuclear changes were more pronounced as compared to conventional PK. In addition, a band of debris with disrupted collagen fibers extending from the anterior to posterior stroma was evident in the corneal stromal layer, compared to very little stromal edema with mechanical trephination



Conventional keratoplasty Femtosecond assisted keratoplasty Femtoseconds laser-assisted keratoplasty (FAK)
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