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Evaluation of inflammatory cytokines during mesenchymal stem cell therapy in type 1 and type 2 diabetic rats /

Lamiaa Mohamed Sayed Ahmed Elalfy

Evaluation of inflammatory cytokines during mesenchymal stem cell therapy in type 1 and type 2 diabetic rats / تقييم السيتوكينات المسببة للإلتهاب أثناء العلاج بالخلايا الجذغية الوسيطة فى الجرذان المصابة بمرض السكرى من النوع الأول والثانى Lamiaa Mohamed Sayed Ahmed Elalfy ; Supervised Alyaa Farid , Neveen Adel - Cairo : Lamiaa Mohamed Sayed Ahmed Elalfy , 2021 - 115 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology

Diabetes mellitus (DM), sometimes known as simply diabetes, is a set of metabolic diseases defined by a persistently high blood sugar level. Frequent urination, increased thirst, and increased hunger are its common symptoms. Diabetes, if left untreated, can lead to several other health issues. Diabetic ketoacidosis, hyperosmolar hyperglycemia, and mortality are all examples of acute complications. Cardiovascular disease, stroke, chronic renal disease, foot ulcers, nerve damage, eye damage, and cognitive impairment are all serious long-term consequences. In 1936, the distinction between type I and type II DM was clearly made. Stem cells are important for living organisms due to their functions of homeostatic tissue maintenance and replacing dysfunctional and senescent cells. Given their remarkable regenerative capacities, stem cells are being applied in treatments for various diseases as a novel potential therapeutic intervention, which is also referred to as regenerative medicine. We aimed to evaluate the efficacy of mesenchymal stem cells (MSCs) in treatment of induced type I and type II diabetic rats. The inflammatory cytokines levels during stem cell therapy were evaluated together with biochemical analysis



Cytokines During mesenchymal stem Type 1 and type 2 diabetic rats
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