Association of Superoxide Dismutase (SOD2 Val16Ala) genetic polymorphism with Cardiac Problems in Egyptian Pediatric Beta-Thalassemia major patients / (Record no. 168196)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04091namaa22004331i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250223033307.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241001s2023 |||a|||fr|m|| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 618.92 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 618.92 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.11.28.M.Sc.2023.Mo.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Mohammed Sayed Ebraheem Awaad, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Association of Superoxide Dismutase (SOD2 Val16Ala) genetic polymorphism with Cardiac Problems in Egyptian Pediatric Beta-Thalassemia major patients / |
| Statement of responsibility, etc. | by Mohammed Sayed Ebraheem Awaad ; Supervised by Prof. Dr. Mona Mohamed Hamdy Mahmoud, Prof. Dr. Iman Abd El-Mohsen Shaheen, Prof. Dr. Rasha Abdel-Raouf Abdel-Aziz |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | ارتباط اشكال التعدد الوراثي لجين الديسموتيز فائق الاكسده (Ala16 Val SOD2) بمشاكل القلب في الاطفال مرضي انيميا البحر المتوسط الكبري المصريين / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 140 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.)-Cairo University, 2023. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 118-140. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | β-Thalassemia major continues to be a major cause of<br/>morbidity and mortality with improving outcome due to advances in<br/>researches and treatments. This study was designed to detect the<br/>association of the antioxidant enzyme Super Oxide Dismutase 2 (SOD2)<br/>Val16Ala (rs4880) genetic polymorphism with cardiac problems in<br/>Egyptian children with β-Thalassemia major.<br/>Results: A total number of 60 pediatric patients with β-Thalassemia<br/>major with age ranged from 8-18 years were genotyped for the SOD2<br/>Val16Ala (rs4880) polymorphism. Also, Echocardiography study was done<br/>to them to assess cardiac problems related to contractility and chambers<br/>size. LVEDD: was high in 10 (38.5%) patients, 8 (26.7%) patients and 2<br/>(50.0%) patients with means 46.12 ± 4.55, 46.97±5.77, 48.50 ±7.51<br/>respectively for AA, AG and GG groups, LVESD: was high in 10 (38.5%)<br/>patients, 8 (26.7%) patients and 2 (50.0%) patients with means of<br/>30.69±4.69, 29.40±6.53, 32.0±7.16 respectively for AA, AG and GG<br/>groups, IVSD: was high in 10 (38.5%) patients, 10 (33.3%) patients and 3<br/>(75%) patients respectively with means 0.83±0.19, 0.84±0.23, 0.98±0.17<br/>for AA, AG and GG groups, LVPWT: was high in 17 (65.4%) patients, 16<br/>(53.3%) patients and 4 (100%) patients respectively with means<br/>0.83±0.19, 0.80 ± 0.15, 1.09±0.25 for AA, AG and GG groups. Regarding<br/>cardiac function: EF was low only in 1 (3.8%) patient in AA group, E/A<br/>ratio: was low only in 1 (25%) patient in GG group. Results showed no<br/>association between SOD2 Val16Ala (rs4880) genetic polymorphism and<br/>cardiac problems with a P-value > 0.05.<br/> |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | أجريت هذه الدراسة على 120 من الاطفال بقسم امراض الدم بمستشفى أبو الريش للاطفال بجامعة القاهرة <br/>اجريت الدراسة لمعرفة العلاقه بين الطفرة الجينية لانزيم الدسموتيز فائق الأكسدة ومشاكل القلب للاطفال المصابون بمرض أنيميا البحر المتوسط الكبرى المصريين.<br/> |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issued also as CD |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pediatrics |
| Source of heading or term | qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thalassemia |
| -- | SOD2 |
| -- | Cardiac Problems |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Mohamed Hamdy Mahmoud |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Abd El-Mohsen Shaheen |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rasha Abdel-Raouf Abdel-Aziz |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2023 |
| Supervisory body | Mona Mohamed Hamdy Mahmoud |
| -- | Iman Abd El-Mohsen Shaheen |
| -- | Rasha Abdel-Raouf Abdel-Aziz |
| Discussion body | Shahira Kamal |
| -- | Amira Abdel Moneim |
| Universities | Cairo University |
| Faculties | Faculty of Medicine |
| Department | Department of Pediatrics |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Eman Ghareeb |
| Reviser Names | Huda |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 01.10.2024 | 88650 | Cai01.11.28.M.Sc.2023.Mo.A | 01010110088650000 | 01.10.2024 | 01.10.2024 | Thesis |