Intensity of Hormone Receptor Expression and Outcome of Hormonal Treatment in Breast Cancer : (Record no. 169667)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04982namaa22004331i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250223033352.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241223s2023 |||a|||f |m|| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.99449 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 616.99449 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.19.04.M.Sc.2023.Mo.I. |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Mohammed Ali Ibrahim Shosha, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Intensity of Hormone Receptor Expression and Outcome of Hormonal Treatment in Breast Cancer : |
| Remainder of title | A Retrospective Egyptian Study / |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | كثافة التعبير فى المستقبلات الهرمونيه ونتائج العلاج في سرطان الثدي / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 144 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.)-Cairo University, 2023. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 108-131. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Worldwide, breast cancer is the most frequently diagnosed <br/>life-threatening cancer in women and the leading cause of cancer death in <br/>women. <br/>Aim of work: To assess the outcome of treatment in breast cancer <br/>according to intensity of hormone receptor expression in breast cancer <br/>patients receiving adjuvant therapy including tamoxifen. <br/>Patients and methods: a retrospective study aiming to assess the outcome <br/>of treatment in breast cancer according to intensity of hormone receptor <br/>expression in breast cancer patients receiving adjuvant therapy including <br/>tamoxifen. Approval was obtained from the Institutional Review Board <br/>(IRB) of the National Cancer Institute, Cairo University. The study will <br/>include about 150 patients of breast cancer with hormone receptor positive <br/>presented to NCI from January 2012 till June 2013. <br/> Results: Of 150 hormone positive breast cancer patients, with median age <br/>at presentation of 48.7 years, were included. Most of them had pathological <br/>stage II (67 patients 44.7%), followed by stage III (72 patients 48%) then <br/>stage I (11 patients 7.3%). The study included 26 patients (17.3 %) with <br/>low ER, 23 patients (15.3%) with moderate ER and 101 patients (67.3%) <br/>with strong ER. There was a significant difference regarding OS, DFS <br/>toward ER expression, P=0.005, 0,006 respectively. Also, there was <br/>significant difference of disease staging regard OS, DFS, P= was 0.001, <br/>0.008, respectively. <br/>Conclusion: hormone positive breast cancer patients with higher ER <br/>expression have better OS and DFS. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | هؤلاء المرضى لديهم فئات عمرية متقاربة ، حيث كان 81 من 150 مريضًا أقل من 50 عامًا (54٪) ، بينما كان 69 مريضًا (46٪) أكثر من 50 عامًا .<br/> معظمهم كان لديهم المرحلة المرضية الثانية (67 مريضا 44.7٪) ، تليها المرحلة الثالثة (72 مريضا 48٪) ثم المرحلة الأولى (11 مريضا 7.3٪).<br/> تم تصنيفها وفقًا لتعبير مستقبلات ER بناءً على درجة Allred ، إلى ER ضعيف أقل من (10٪) ، ER ضعيف (من 11 إلى 50٪) و ER قوي (أكثر من 50٪)<br/> تضمنت دراستنا 26 من 150 مريضًا (17.3٪) يعانون من انخفاض ER ، و 23 مريضًا (15.3٪) من ER المعتدل و 101 مريضًا (67.3٪) من ER القوي ، وقيمة P (0.04).<br/>لم نجد أي فروق ذات دلالة إحصائية بين تعبير ER والمراحل المرضية للمرض كانت القيمة p 0.6 أو تعبير ER والعمر ، وكانت القيمة p 0.3<br/>ما توصل إليه البحث <br/>1- السيدات اللاتي تصبن بأورام الثدي الهرموني الإيجابي , كلما زاد تعبير المستقبلات الهرمونية , كلما تحسنت النتائج الخاصة بالبقاء على قيد الحياة <br/>2- كلما زادت المرحلة المرضية لأورام الثدي كلما ساءت النتائج الخاصة بالبقاء على قيد الحياة<br/>3- لا يعتمد معدل تعبير المستقبلات الهرمونية على عوامل معينة مثل السن ومرحلة المرض . |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issued also as CD |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Breast cancer |
| Source of heading or term | qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Breast cancer |
| -- | Hormone positive |
| -- | Cancer in women |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rabab Mohammed Gaafar |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mosaad Mahmoud El Gammal |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Loay Hussein |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2023 |
| Supervisory body | Rabab Mohammed Gaafar |
| -- | Mosaad Mahmoud El Gammal |
| -- | Iman Loay Hussein |
| Universities | Cairo University |
| Faculties | Faculty of National Cancer Institute |
| Department | Department of Medical oncology |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Nourhan |
| Reviser Names | Huda |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 23.12.2024 | 89582 | Cai01.19.04.M.Sc.2023.Mo.I. | 01010110089582000 | 23.12.2024 | 23.12.2024 | Thesis |