MARC details
| 000 -LEADER |
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| fixed length control field |
05819namaa22004331i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - أخر تعامل مع التسجيلة |
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| control field |
20250624110449.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250513s2024 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloguing agency |
EG-GICUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GICUC |
| Modifying agency |
EG-GICUC |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract |
eng |
| -- |
ara |
| 049 ## - Acquisition Source |
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| Acquisition Source |
Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
546.3 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) |
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| Classification number |
546.3 |
| Edition number |
21 |
| 097 ## - Degree |
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| Degree |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| Local Call Number |
Cai01.12.09.M.Sc.2024.Mo.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Authority record control number or standard number |
Mostafa Ali Mostafa Ahmed El-Gendi, |
| Preparation |
preparation. |
| 245 10 - TITLE STATEMENT |
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| Title |
Preparation and structural characterization of some metal complexes derived from schiff base ligands and their applications / |
| Statement of responsibility, etc. |
by Mostafa Ali Mostafa Ahmed El-Gendi ; Supervisors Prof. Dr. Mohamed Mohamed Ahmed Omar, Dr. Reem Gamal Deghadi, Dr. Yassmine Mamdouh Huessien Ahmed. |
| 246 15 - VARYING FORM OF TITLE |
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| Title proper/short title |
تحضير وتوصيف تركيبي لبعض متراكبات الفلزات المشتقة من ليجندات قواعد شيف و تطبيقاتها / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Date of production, publication, distribution, manufacture, or copyright notice |
2024. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
154 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
25 cm. + |
| Accompanying material |
CD. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Source |
rda content |
| 337 ## - MEDIA TYPE |
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| Media type term |
Unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
volume |
| Source |
rdacarrier |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliography: pages 137-151. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Schiff bases and their metal complexes are versatile compounds with wide-ranging applications in both industrial and biological contexts. In this study, two novel Schiff bases, (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione condensed with furfuryl amine in a 1:1 ratio (H2L1) and (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione condensed with 2-Aminomethyl-pyridine in a 1:1 ratio (H2L2), along with their complexes with Cr(III), Ni(II), Fe(III), Co(II), Mn(II), Zn(II), Cu(II), and Cd(II) metal ions, were synthesized and thoroughly characterized using various analytical techniques. The chelates exhibited octahedral geometry, as revealed by elemental analyses, mass spectrometry, FT-IR, 1H-NMR, molar conductivity, and thermal analyses techniques (TG and DTG). Moreover, the in vitro antibacterial activity of the ligands and their complexes was screened, showcasing their potential in combating bacterial infections. Computational studies using the DFT/B3LYP method provided insights into the molecular structures of the Schiff base ligands. Additionally, molecular docking studies were conducted to explore the interactions between the synthesized compounds and different protein receptors, shedding light on their potential biological activities. The antibacterial activities of the Schiff bases (H2L1 and H2L2) were evaluated, and antioxidant activity was measured, further highlighting the multifaceted nature and potential applications of Schiff bases and their metal complexes in both industrial and biomedical fields. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
القواعد الشيف ومتراكباتها مع الفلزات هي مركبات متعددة الاستخدامات بتطبيقات واسعة في السياقين الصناعي والبيولوجي. في هذه الدراسة، تم تحضير قاعدتي شيف جديدتين، (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione المكثفة مع الفورفوريل-أمين بنسبة 1:1 (H2L1) و (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione المكثفة مع امينوبيريدين 2-Aminomethyl بنسبة 1:1 (H2L2)، بالإضافة إلى متراكباتها مع أيونات الفلزات Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), و Cd(II)، وتم توصيفها بشكل شامل باستخدام تقنيات تحليلية متعددة. أظهرت المتراكبات هندسة ثمانية أوجه، كما كشفت عنها التحاليل العنصرية، وطيف الكتل، والأشعة تحت الحمراء بالموجات الفوق صوتية، والرنين النووي المغناطيسي، والتحليل الحراري. علاوة على ذلك، تم فحص النشاط المضاد للبكتيريا في المختبر للمركبات الأساسية ومتراكباتها، مما يظهر إمكانيتها في محاربة العدوى البكتيرية. قدمت الدراسات الحوسبية باستخدام الطريقة DFT/B3LYP نظرة عميقة في الهياكل الجزيئية لقواعد شيف. تم إجراء دراسات الربط الجزيئي أيضًا لاستكشاف التفاعلات بين المركبات المصنعة ومستقبلات البروتين المختلفة، مما ألقى الضوء على الأنشطة البيولوجية المحتملة لها. تم تقييم النشاط المضاد للبكتيريا لقواعد الشيف (H2L1 و H2L2)، وقياس النشاط المضاد للأكسدة، مما يسلط المزيد من الضوء على الطبيعة متعددة الجوانب والتطبيقات المحتملة لقواعد الشيف ومتراكباتها مع الفلزات في الحقول الصناعية والطبية. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Issues CD |
Issues also as CD. |
| 546 ## - LANGUAGE NOTE |
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| Text Language |
Text in English and abstract in Arabic & English. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Metallic compounds |
| Source of heading or term |
qrmak |
| 653 #0 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Schiff base complexes |
| -- |
Thermal analyses (TG and DTG) |
| -- |
DFT |
| -- |
antibacterial activity |
| -- |
antioxidant activity |
| -- |
Molecular docking studies |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mohamed Mohamed Ahmed Omar |
| Relator term |
thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Reem Gamal Deghadi |
| Relator term |
thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yassmine Mamdouh Huessien Ahmed |
| Relator term |
thesis advisor. |
| 900 ## - Thesis Information |
|---|
| Grant date |
01-01-2024 |
| Supervisory body |
Mohamed Mohamed Ahmed Omar |
| -- |
Reem Gamal Deghadi |
| -- |
Yassmine Mamdouh Huessien Ahmed |
| Universities |
Cairo University |
| Faculties |
Faculty of Science |
| Department |
Department of Chemistry |
| 905 ## - Cataloger and Reviser Names |
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| Cataloger Name |
Shimaa |
| Reviser Names |
Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
| Edition |
21 |
| Suppress in OPAC |
No |