Image-guided breast conserving surgery : (Record no. 172484)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 07421namaa22004451i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250723130152.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250610s2024 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.99449059 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 616.99449059 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.19.04.Ph.D.2024.Mi.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Michael Farid Fouad Abdelmalik, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Image-guided breast conserving surgery : |
| Remainder of title | A Randomized Controlled Trial / |
| Statement of responsibility, etc. | by Michael Farid Fouad Abdelmalik ; Supervisors Prof. Sherif Naguib, Prof. Ahmed Farahat, Dr. Tarek Hashim, Dr. Amira Hamed Radwan. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الاستئصال التحفظي للثدي عن طريق الأشعة |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 80 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 61-80. |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Background: Breast-conserving surgery (BCS) has gained wide acceptance as the treatment of choice for early-stage breast cancer. One of the primary goals of BCS is to obtain tumor-free resection margins. In practice, the excision of a palpable breast carcinoma is guided by preoperative diagnostic images and the intraoperative tactile skills of the surgeon. The somewhat ‘blind’ approach of using palpation-guided surgery is known to be highly inaccurate, with studies worldwide reporting positive resection margins in up to 41% of patients. In recent years, ultrasonography has emerged as an effective guidance tool during surgery and ultrasound-guided surgery has been introduced into breast cancer surgery as a method of excising nonpalpable breast cancer. In light of the advantages when applied to nonpalpable masses, ultrasound-guided surgery for palpable breast cancer should similarly decrease margin positivity and excision volumes.<br/>Objective: The aim of this study is comparing ultrasound-guided vs palpation-guided conservative breast surgery in obtaining tumor-free resection margins and achieving a satisfactory cosmetic outcome.<br/> Methods: This study was a prospective randomized controlled clinical trial where patients with early breast cancer (T1-T2) and eligible for breast conserving surgery are randomly assigned (1:1) into two arms. Arm A: included the patients who will undergo ultrasound-guided breast conserving surgery. Arm B: included the patients who will undergo the conventional palpation-guided breast conserving surgery.<br/>Results: Overall, 142 patients undergoing breast conserving surgery were enrolled: 71 were allocated to the Ultrasound-guided (US) group (Arm A) and 71 to the Palpation-guided (PG) group (Arm B).<br/>Patient and tumor characteristics were comparable between the two groups. Age, Body mass index, tumor laterality, tumor location and tumor stage were comparable in both groups and statistically insignificant.<br/>Despite that the final tumor size was comparable between both groups, IOUS significantly reduced the main specimen volume and the least negative margin width (p<0.001). The median operative time was significantly longer in the US group bey around 27 min than in the PG group and this was statistically significant in favor of the PG surgery (p<0.001). The involved resection margin rate was significantly higher in the PG group and thus the need for reoperation (p<0.001). Postoperative complications rate was also comparable between the US group and the PG group. As regards the cosmetic results, patients filled out a self-evaluation questionnaire and the data was interpreted using BCCT.core software. The results were highly in favour of the US group with more patient satisfaction and better results than in the PG group (p<0.001).<br/>Conclusion: IOUS is the only method allowing a true real-time visualization and continuous control of resection margins during all phases of BCS. In our single-institution study, IOUS demonstrated clear superiority over palpation-guided surgery in both oncological and surgical outcomes except for the operative time (smaller excision volume yet, with optimum resection margins and better cosmetic outcome). IOUs provides much better tumor localization in small breasts with dense fibroadenosis. Since all the other available localization techniques (including palpation) limit the surgeon’s visual guidance during BCS, IOUS could be regarded as one of the most significant modern technological innovations in the field of breast cancer surgery, restoring sight to the breast surgeon. Our findings strongly suggests that the integration of IOUS in breast conserving surgery could be regarded as a highly beneficial surgical approach. |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | اكتسبت الجراحة التحفظية للثدي قبولًا واسعًا باعتبارها العلاج المفضل لسرطان الثدي في المراحل المبكرة على مدى العقود الماضية، تم تحقيق تقدم في التشخيص المبكر من خلال زيادة وعي المريض، وتصوير الثدي بالأشعة السينية على نطاق واسع وتقنيات التصوير المحسنة. وقد أدى ذلك إلى زيادة في معدل الاستئصال التحفظي للثدي ويمكن الآن تقديم هذه الإجراءات بأمان لمعظم مرضى سرطان.<br/>الثدي. أحد الاهداف الرئيسية للاستئصال التحفظي للثدي هو الحصول على حواف امان خالية من الورم. ومن الاهداف الثانوية المهمة هو تحقيق نتيجة تجميلية مرضية. حظيت النتيجة التجميلية للجراحة التحفظية للثدي باهتمام متزايد في السنوات الأخيرة.<br/>بسبب العلاقة الوثيقة مع رفاهية المريض ونوعية الحياة. سيتم تصميم هذه الدراسة لمقارنة فعالية الجراحة الموجهة عن طريق الموجات الصوتيه في سرطان الثدي الغازي الملموس مع الجراحة المعيارية الموجهه بالجس بما في ذلك النتائج الرئيسية لحواف الامان المرتبطة بالورم وكميه الانسجة السليمة المستأصلة مع الورم. وكذلك الأهداف الثانوية من تقييم النتيجة التجميلية للجراحة باستخدام كل من التقييم الذاتي للمريض والتقييم عن طريق برنامج BCCT.Core. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | breast surgery |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | breast cancer |
| -- | image |
| -- | guided |
| -- | surgical margin |
| -- | palpation-guided |
| -- | breast |
| -- | conserving |
| -- | frozen |
| -- | cosmetic outcome |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sherif Naguib |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Farahat |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tarek Hashim |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amira Hamed Radwan |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Sherif Naguib |
| -- | Ahmed Farahat |
| -- | Tarek Hashim |
| -- | Amira Hamed Radwan |
| Universities | Cairo University |
| Faculties | National Cancer Institute |
| Department | Department of surgical oncology |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 10.06.2025 | 91371 | Cai01.19.04.Ph.D.2024.Mi.I | 01010110091371000 | 10.06.2025 | 10.06.2025 | Thesis |