Analytical Study of Some Drugs Treating Respiratory Tract Diseases / (Record no. 172732)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04295namaa22004091i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250804120245.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250625s2024 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.19 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 615.19 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.08.05.Ph.D.2024.Ya.A. |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Yasmin Mohamed Youssef Emam, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Analytical Study of Some Drugs Treating Respiratory Tract Diseases / |
| Statement of responsibility, etc. | By Yasmin Mohamed Youssef Emam; Supervised By Prof. Dr. Marianne Alphonse Mahrouse, |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة تحليلية لبعض الأدوية المعالجة لأمراض الجهاز التنفسي / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 145 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 137-145. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | In this thesis, fast, simple and sensitive analytical techniques were established for determining various drugs that influence the respiratory system.<br/>These drugs include glycopyrronium bromide, indacaterol acetate, mometasone furoate and selexipag. The drugs were analyzed in bulk, in pharmaceutical formulations, binary mixtures, ternary mixtures, and in presence of impurities. Also, the greenness assessment was performed using four metrices NEMI, ESA, GAPI and AGREE, the results were compared with that of previously published ones<br/>A stability indicating reversed phase high performance liquid chromatography (RP- HPLC/UV) method was developed for the determination of selexipag in presence of its impurities.<br/>Another reversed phase high performance liquid chromatography (RP-HPLC/UV) method was developed and validated for the simultaneous determination of glycopyrronium bromide, indacaterol acetate and mometasone furoate in their fixed dose combination inhaler using experimental design technique by applying Plackett–Burman and face-centered composite design (FCC).<br/>Four sensitive and accurate UV-spectrophotometric methods were developed the simultaneous determination of indacaterol acetate and mometasone furoate. These methods were induced dual wavelength spectrophotometric method, absorption factor method coupled with modified amplitude subtraction method, first derivative spectrophotometric method coupled with amplitude factor method and first derivative ratio spectrophotometric method.<br/>At the end of each section, the validation parameters according to ICH guidelines were summarized. In addition, a statistical comparison between the results of the developed methods and that of the pharmacopeial or reported methods was performed and no significant difference were found. <br/> |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | تم فى هذه الرسالة إستحداث طرق تحليلية مختلفة على درجة من الدقة والسرعة والحساسية للتقدير الكمي لبعض الأدوية المؤثرة على الجهاز التنفسي وهي: سيليكسيباج وجلايكوبيرونيام بروميد وإينداكاتيرول أسيتات وموميتازون فوروات في صورتها النقية وفى مخاليطيها ومع نواتج تحللها وفى مستحضراتها الصيدلية ومقارنتها بالطرق الدستورية أو المرجعية. كما تم دراسة الأثر البيئي للطرق المقترحة باستخدام أربعة طرق وتمت مقارنة النتائج بنتائج الطرق المنشورة سابقا وأثبتت النتائج ان الطرق المقترحة صديقة للبيئة. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issued also as CD |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmaceutical Chemistry |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Glycopyrronium bromide |
| -- | indacaterol acetate |
| -- | mometasone furoate |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marianne Alphonse Mahrouse |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Marianne Alphonse Mahrouse |
| Universities | Cairo University |
| Faculties | Faculty of Pharmacy |
| Department | Department of Pharmaceutical Chemistry |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Eman El gebaly |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 25.06.2025 | 91537 | Cai01.08.05.Ph.D.2024.Ya.A. | 01010110091537000 | 25.06.2025 | 25.06.2025 | Thesis |