New methods for determination of Metoclopramide and Xylometazoline hydrochlorides pharmaceutical compounds / (Record no. 172931)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05190namaa22004211i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250707115355.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250707s2024 ua a|||fr|m|| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 547.3 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 547.3 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.12.08.Ph.D.2024.Ma.N. |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Manal Salah El-Din El Ayoubi Mohammed Ashour, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | New methods for determination of Metoclopramide and Xylometazoline hydrochlorides pharmaceutical compounds / |
| Statement of responsibility, etc. | By Manal Salah El-Din El Ayoubi Mohammed Ashour; Under the Supervision of Prof. Dr. Yousry Moustafa Issa, Dr. Waheed Fathi El-Hawary |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | طرق مستحدثة لتقدير المركبات الدوائية الميتوكلوبراميد و الزيلوميتازولين هيدروكلورايد / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 618 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 547-607. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | This work has been carried out to present and characterize new indirect atomic absorption spectrophotometric (AAS) and electrometric (conductometric and chemically modified carbon paste ion-selective electrodes (CMCPEs)) methods for the determination of the two drugs named xylometazoline hydrochloride (XMZ.HCl) and metoclopramide hydrochloride (MCP.HCl). New CMCPEs sensitive for drugs were constructed. They are based on ion-association of drug cation with anions of phosphotungstate and silicotungstate, according to the calculated molar ratios. The solubility and the solubility products of these ion-associates were determined conductometrically. The electrodes were constructed and fully characterized. Several effects affecting on the performance characteristics of the new electrodes were studied. The best sensors were used to perform potentiometric determination of the drug cations by potentiometric titration. New conductometric titration method for the determination of the above mentioned drugs was developed. The conductometric method involves determination of the two drugs by titration against standard solution of sodium tetraphenylborate or ammonium reineckate. The study includes the different factors affecting the conductometric detection of the end point. Factors affecting the solubility of drug-reineckate ion-pairs by AAS were studied and indirect AAS method for determination of both drugs was also applied. All results obtained by the three methods were treated statistically and were in good agreement with the pharmacopoeial and reference methods. Intracomparison of the three new methods was also performed. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | تشتمل هذه الدراسة علي بحث مرجعي لإثنين من الأدوية و هما (زيلوميتازولين هيدروكلورايد) و (ميتوكلوبراميد هيدروكلورايد) وإيجاد طرق كهروكيميائية جديدة لتقديرهما و إيجاد طريقة جديدة للقياس الطيفي الإمتصاصي الذري الغير مباشر. تعتمد الطريقة الأولي علي تصنيع مجسات انتقائية تقوم علي فكرة عجينة الكربون المعدلة كيميائيآ. و لقد تم إدماج المادة النشطة بداخل عجينة الكربون السالف ﺫكرها. أما المادة النشطة فتتكون كنتيجة لدمج أيون الزيلوميتازولين أو الميتوكلوبراميد مع الفوسفوتنجستات و السليكوتنجستات بنسب مولارية محددة و تعتبر طريقة قياس التوصيلية الكهربية هي الطريقة الثانية لتقدير هذين الدوائين عن طريق ترسيبهما باستخدام رباعي فينيل بورات الصوديوم و رينيكات الأمونيوم. كما تم تقدير الدوائين بطريقة غير مباشرة باستخدام القياس الطيفي للإمتصاص الذري و ذلك عن طريق إضافة كمية زائدة من رينيكات الأمونيوم إلي الدواء بهدف ترسيبه كاملآ ثم تقدير عنصر الكروم الذائد في الرشح بهدف طرحه من الكروم الكلي المضاف و ذلك من أجل تقدير الدواء بطريقة غير مباشرة. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issued also as CD |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Analytical chemistry |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | xylometazoline hydrochloride (XMZ.HCl) |
| -- | metoclopramide hydrochloride (MCP.HCl) |
| -- | atomic absorption spectrophotometry (AAS) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yousry Moustafa Issa |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Waheed Fathi El-Hawary |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Yousry Moustafa Issa |
| -- | Waheed Fathi El-Hawary |
| Universities | Cairo University |
| Faculties | Faculty of Science |
| Department | Department of Chemistry |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Nourhan |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
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| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 07.07.2025 | 91488 | Cai01.12.08.Ph.D.2024.Ma.N. | 01010110091488000 | 07.07.2025 | 07.07.2025 | Thesis |