Effect of intranasal midazolam versus ketamine midazolam combination as a premedication in children undergoing tonsillectomy and adenoidectomy on the occurrence of postoperative respiratory adverse events : (Record no. 173890)
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| fixed length control field | 06497namaa22004571i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20250925123017.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250903s2024 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposite |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 617.96 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 617.96 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.11.01.Ph.D.2024.Ma.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Maha Gebreel Ahmed Hefny, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of intranasal midazolam versus ketamine midazolam combination as a premedication in children undergoing tonsillectomy and adenoidectomy on the occurrence of postoperative respiratory adverse events : |
| Remainder of title | a double-blind, randomized controlled trial / |
| Statement of responsibility, etc. | by Maha Gebreel Ahmed Hefny ; Supervisors Prof. Nevine Mahmoud Gouda, Prof. Hany Mohammed El-Hadi Shoukat, Prof. Khaled Abdel Fattah Sarhan, Dr. Kareem Mohammed Assem Nawwar. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير عقار الميدازولام داخل الأنف مقابل تركيبة عقار الكيتامين و الميدازولام كدواء تمهيدي فى الأطفال الذين يخضعون لاستئصال اللوزتين و استئصال الغدد اللمفاوية على حدوث الأحداث السلبية التنفسية بعد الجراحة : |
| Remainder of title | تجربة عشوائية مزدوجة التعمية / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 67 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 48-62. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Aim of Work: To investigate the effect of addition of intranasal ketamine to midazolam compared to midazolam alone as a premedication on the occurrence of PRAEs.<br/>Patients: Children ASA I&II aged from 3 to 12 years old undergoing AT procedures. <br/>Interventions: The study was a double-blinded randomized controlled trial. 202 Children were randomly assigned to two groups in a 1d1d1 ratio; Group Midazolam (Group M) was to receive sedation by intranasal midazolam before general anesthesia and Group midazolam-ketamine (Group M-K) was to receive intranasal midazolam-ketamine before general anesthesia.<br/>Measurements: Perioperative respiratory adverse events were clustered into two groups: Major as (bronchospasm, laryngospasm, hypoxia [so2 less than 90%], airway obstruction and stridor). Minor as (cough, desaturation from [90%-95%]). Heart rate, mean arterial pressure, and pulse oximeter saturation were recorded. Sedation success rate was recorded using FUNK score, and the post-operative Anxiolysis score was used to assess sedation. Pain was assessed after extubation and at PACU every 30 minutes till discharge using Wong-Baker Pain Scale. Postoperative emergence delirium was assessed using PAED scale.<br/><br/><br/>Results: 199 patients were included in this study, the incidence of PRAEs was lower in midazolam-ketamine group (Group M-K) compared to midazolam group (Group M) alone. The combination group also improved postoperative pain control, higher sedation success rate, and comparable recovery scores, with no significant adverse events related to ketamine administration. <br/>Conclusion: In children undergoing adenotonsillectomy, the preoperative intranasal combination of ketamine and midazolam effectively reduced the incidence of perioperative respiratory adverse events compared to intranasal midazolam alone, without significant adverse events related to ketamine. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | استئصال اللوزتين الغدية هو واحد من أكثر العمليات الجراحية شيوعا بين الأطفال. يمكن أن يعاني الأطفال الذين يخضعون لجراحات التكنولوجيا المساعدة من قلق وضيق كبيرين خلال الفترة المحيطة بالجراحة. من ناحية أخرى ، فإن الأحداث الضائرة التنفسية المحيطة بالجراحة هي المضاعفات الأكثر شيوعا أثناء تخدير الأطفال.<br/>هدفت هذه الدراسة إلى التحقيق في تأثير إضافة الكيتامين داخل الأنف إلى الميدازولام مقارنة بالميدازولام وحده كتخدير على حدوث الأحداث الضائرة التنفسية المحيطة بالجراحة.<br/>تم تسجيل ما مجموعه 199 طفلا في هذه التجربة المعشاة ذات الشواهد. وكانت النتيجة الأولية هي حدوث أي أحداث ضائرة تنفسية في الفترة المحيطة بالجراحة.<br/>أظهرت النتائج أن الجمع بين الكيتامين والميدازولام قلل بشكل كبير من حدوث الاحداث الضئرة التنفسية المحيطة بالجراحة مقارنة بالميدازولام وحده. الأهم من ذلك ، أن تركيبة مجموعة الكيتامين ميدازولام لم تسفر عن آثار ضارة كبيرة تتعلق باستخدام الكيتامين.<br/> في الختام ، يعد التخدير عن طريق الأنف مع تركيبة الكيتامين ميدازولام أكثر فعالية من الميدازولام وحده في الحد من الأحداث الضائرة التنفسية المحيطة بالجراحة لدى الأطفال الذين يخضعون لاستئصال اللوزتين واستئصال اللحمية ، مما يوفر استراتيجية أكثر أمانا وفعالية قبل الجراحة. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anesthesia |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | التخدير |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Adenotonsillectomy |
| -- | Intranasal Midazolam |
| -- | Intranasal Midazolam-ketamine |
| -- | Sedation |
| -- | Preoperative |
| -- | Respiratory Adverse Events |
| -- | pediatrics |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nevine Mahmoud Gouda |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hany Mohammed El-Hadi Shoukat |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khaled Abdel Fattah Sarhan |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kareem Mohammed Assem Nawwar |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Nevine Mahmoud Gouda |
| -- | Hany Mohammed El-Hadi Shoukat |
| -- | Khaled Abdel Fattah Sarhan |
| -- | Kareem Mohammed Assem Nawwar |
| Universities | Cairo University |
| Faculties | Faculty of Medicine |
| Department | Department of Anesthesia, Surgical ICU and Pain Management |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 03.09.2025 | 91972 | Cai01.11.01.Ph.D.2024.Ma.E | 01010110091972000 | 03.09.2025 | 03.09.2025 | Thesis |