MARC details
| 000 -LEADER |
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| fixed length control field |
07093namaa22004331i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - أخر تعامل مع التسجيلة |
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| control field |
20251103102339.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
251021s2025 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloguing agency |
EG-GICUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GICUC |
| Modifying agency |
EG-GICUC |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract |
eng |
| -- |
ara |
| 049 ## - Acquisition Source |
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| Acquisition Source |
Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
579.135 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) |
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| Classification number |
579.135 |
| Edition number |
21 |
| 097 ## - Degree |
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| Degree |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| Local Call Number |
Cai01.12.05.M.Sc.2025.Na.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Authority record control number or standard number |
Nahla Muhammed Mahmoud Ahmed Ghazy, |
| Preparation |
preparation. |
| 245 10 - TITLE STATEMENT |
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| Title |
Efficacy of natural compounds and nanoparticles in control of dermatophytes / |
| Statement of responsibility, etc. |
by Nahla Muhammed Mahmoud Ahmed Ghazy ; Supervisor Prof. Dr. Mohsen Abou El- Ela Sayed, Prof. Dr. Assma Ali Hamouda. |
| 246 15 - VARYING FORM OF TITLE |
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| Title proper/short title |
كفاءة المركبات الطبيعية و الجزيئات النانوية فى مقاومة الفطريات الجلدية |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Date of production, publication, distribution, manufacture, or copyright notice |
2025. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
59 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
25 cm. + |
| Accompanying material |
CD. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Source |
rda content |
| 337 ## - MEDIA TYPE |
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| Media type term |
Unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
volume |
| Source |
rdacarrier |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc)-Cairo University, 2025. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliography: pages 51-59. |
| 520 #3 - SUMMARY, ETC. |
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| Summary, etc. |
Dermatophyte infections globally account for twenty to twenty-five percent of fungal infections. Dermatophytes have begun exhibiting antifungal drug resistance, making it challenging to treat this particular infection. For this reason, researchers are looking for alternative treatments. Essential oils could be used as alternative solutions as they have been used for a long period to treat different infections. Nanoparticles are of tremendous interest in various applications including antifungal agents. With their inveterate antifungal action, many metallic nanoparticles have been utilized against human and plant pathogenic fungi. The research has demonstrated the antifungal efficacy of cinnamon, clove, lemongrass, tea tree, thyme, and garlic essential oils, and the impact of their combinations was assayed against Microsporum canis, Trichophyton tonsurans, T. violaceum, T.<br/>verrucosum and Epidermophyton floccosum. Polymerase Chain Reaction (PCR) – Restriction Fragment Length Polymorphism (RFLP) was used to identify the most prevalent M. canis. The accession number of M. canis was obtained as ON007275. All tested essential oils exhibited anti-dermatophytic action except garlic. A synergistic effect was attained by cinnamon + clove, cinnamon + lemongrass, clove<br/>+ lemongrass, clove + tea tree, and thyme + tea tree combinations. Concerning antifungal activity, M. canis was the most susceptible dermatophytic species, except in the case of thyme T. violaceum, which was the most susceptible dermatophytic species. The maximum inhibition was recorded in the cases of cinnamon and cinnamon + lemon grass combination against M. canis. The least minimum inhibitory concentrations were attained by cinnamon and clove against M. canis, cinnamon + clove against M. cainis, and T. violaceum, and cinnamon + lemon grass against M. cainis, T. violaceum, T. verrucosum and E. floccosum. The least Minimum Fungicidal Concentration showed by cinnamon against M. canis, cinnamon + clove against M. canis, and T. violaceum, cinnamon + lemongrass against M. cains T. violaceum, T. verrucosum, and E. floccosum, clove + lemongrass against M. canis. The current research has tested the antifungal efficacy of eight novel synthesized metallic nanoparticle compounds: Ag0.49Cr2.51O4, Ag0.99Fe1.01O3, CoLa0.019Fe1.981O4, Co0.99Fe1.99O4, Ag0.99Cr1.01O2, Ca0.99Fe1.99O4, CoBi0.019Fe1.981O4,<br/>and Cu0.99Fe1.99O4 were synthesized by a flash auto-combustion reaction to evaluate synergistic potential of the Np's exhibited antifungal activity in combination with cinnamon, clove, lemongrass, tea tree and thyme essential oils extracted by Soxhlet method against M. canis, T. tonsurans, T. violaceum, T. verrucosum, and E. floccosum. Four nanoparticle compounds exhibited antifungal activity: silver chromite, silver iron oxide, cobalt lanthanum ferrite, and cobalt iron oxide against all tested dermatophytes. Maximum inhibition was recorded in the cases of Ag0.99Fe1.01O3, Ag0.99Fe1.01O3 + cinnamon against M. canis. Least minimum inhibitory concentrations were attained by Cinnamon against M. canis, Ag0.99Fe1.01O3 against M. canis, T. tonsurans, and T. violaceum, Ag0.99Fe1.01O3 + cinnamon against<br/>M. canis, T. violaceum and, T. verrucosum , Ag0.99Fe1.01O3 + clove, and Ag0.99Fe1.01O3 + lemongrass against M. canis. The study showed promising results regarding the synergistic antifungal efficacy of nanoparticle compounds combined with essential oils in the cases of Ag0.99Fe1.01O3 with cinnamon, Ag0.99Fe1.01O3 with clove and Ag0.99Fe1.01O3 with lemon grass against all tested dermatophytes |
| 520 #3 - SUMMARY, ETC. |
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| Summary, etc. |
وأظهرت الدراسة وجود نشاط معادٍ للفطريات الجلدية في خمسة زيوت طيارة إستُخرجت بطريقة Soxhelet وهي: القرفة , القرنفل, حشيشة الليمون, شجرة الشاى, الزعتر ضد Microsporum canis, Trichophyton tonsurans, T. violaceum, T. verrucosum, and Epidermophyton floccosum وقد يكون الأثر التآزري المضاد للفطريات الناجم عن تشاركات الزيوت الطيارة إستراتيجية واعدة للتغلب على القيود العلاجية للأدوية المضادة للفطريات وتحقق أثر تآزري من خلال القرفة مع القرنفل، والقرفة مع حشيشة الليمون، والقرنفل مع حشيشة الليمون ، والقرنفل مع شجرة الشاي، والزعترمع شجرة الشاي. وقد أظهرت الدراسة وجود نشاط مضاد للفطريات الجلدية لأربعة مركابات نانوية جديدة مصنعة و هى: Ag0.49Cr2.51O4, Ag0.99Fe1.01O3, CoLa0.019Fe1.981O4, and Co0.99Fe1.99O4 ضد Microsporum canis, Trichophyton tonsurans, T. violaceum, T. verrucosum, and Epidermophyton floccosum , والنتائج الواعدة فيما يتعلق بالفعالية التآزرية المضادة للفطريات للزيوت الطيارة بالإتحاد مع المركبات النانوية في حالات :القرفة مع Ag0.99Fe1.01O3, القرنفل مع Ag0.99Fe1.01O3 , حشيشة الليمون مع Ag0.99Fe1.01O3 ضد Microsporum canis, Trichophyton tonsurans, T. violaceum, T. verrucosum, and Epidermophyton floccosum |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Issues CD |
Issues also as CD. |
| 546 ## - LANGUAGE NOTE |
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| Text Language |
Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Mycology |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
علم الفطريات |
| 653 #1 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Antifungal activity |
| -- |
Essential oils |
| -- |
Nanoparticles |
| -- |
Synergistic combinations |
| -- |
Minimum inhibitory concentration (MIC) |
| -- |
Dermatophytes |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mohsen Abou El- Ela Sayed |
| Relator term |
thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Assma Ali Hamouda |
| Relator term |
thesis advisor. |
| 900 ## - Thesis Information |
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| Grant date |
01-01-2025 |
| Supervisory body |
Mohsen Abou El- Ela Sayed |
| -- |
Assma Ali Hamouda |
| Universities |
Cairo University |
| Faculties |
Faculty of Science |
| Department |
Department of Botany and Microbiology |
| 905 ## - Cataloger and Reviser Names |
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| Cataloger Name |
Shimaa |
| Reviser Names |
Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
| Edition |
21 |
| Suppress in OPAC |
No |