The impact of climatic changes on the epidemiology of some emerging zoonotic pathogens / (Record no. 175179)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 08969nam a22004457a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20251025120152.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251025s2025 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 636.089 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 636.089 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.10.18.M.Sc.2025.Ay.i |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Aya Atef Ibrahim Elbadawy, |
| Preparation | preparation. |
| 245 14 - TITLE STATEMENT | |
| Title | The impact of climatic changes on the epidemiology of some emerging zoonotic pathogens / |
| Statement of responsibility, etc. | by Aya Atef Ibrahim Elbadawy ; Supervisors Prof. Dr. Maha Ahmed Sabry, Prof. Dr. Dalia Anwar Hamza, Dr. Zeinab Said Ahmed. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | ﺗﺄﺛﯿﺮ اﻟﺘﻐﯿﺮات اﻟﻤﻨﺎﺧﯿﺔ ﻋﻠﻰ وﺑﺎﺋﯿﺎت ﺑﻌﺾ اﻷﻣﺮاض اﻟﻤﺸﺘﺮﻛﺔ اﻟﻄﺎرﺋﺔ |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 142 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc)-Cairo University, 2025. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 118-141. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Although aquaculture is essential to the world's food security, climate change is having a greater impact on it since it changes the ecosystem, impairs fish health, and increases the danger of illness. Antimicrobial- resistant (AMR) bacteria, such as Pseudomonas aeruginosa (P. aeruginosa) and Escherichia coli (E. coli), are spreading due to rising temperatures and pH variations, endangering public health and food safety. Thus, 328 Nile Tilapia (Oreochromis niloticus) from Egyptian fish farms were gathered and categorized according to environmental and seasonal fluctuations. P. aeruginosa and E. coli were isolated and identified using molecular techniques. P.aeruginosa was highly prevalent (95.12%) in all fish groups, reaching its peak in the summer, and its virulence genes, such as exoS, ToxA, oprL, and phzM, increased with temperature. Investigating the genes for β- lactamase and carbapenemase resistance using PCR showed that blaTEM and blaOXA-48 dominated were most frequent in the summer, and phylogenetic analysis linked P. aeruginosa isolates to humans associated strains. The prevalence of E. coli was notably high (92.68%) and showed a strong correlation with increased water temperatures. Diarrheagenic E. coli was detected in 82.1% of the samples, with enterotoxigenic E. coli (ETEC) identified as the predominant (86.84%) pathotype.<br/> <br/>Hybrid strains carrying multiple virulence markers were detected, and resistance genes such as blaTEM, blaCTX-M, and blaOXA-48 were widespread in warmer months. Environmental stressors, including temperature and pH fluctuations, contributed to increased resistance and virulence in both bacterial species. Rising temperatures and pH imbalances, likely driven by climate change, contribute to increased bacterial virulence and antimicrobial resistance in aquaculture. This study highlights the need for proactive management, including routine monitoring and improved sanitation, to mitigate these risks and ensure sustainable aquaculture and public health safety. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | ﺗﻌﺪ ﺗﺮﺑﯿﺔ اﻷﺣﯿﺎء اﻟﻤﺎﺋﯿﺔ ﺿﺮورﯾﺔ ﻟﻸﻣﻦ اﻟﻐﺬاﺋﻲ ﻋﺎﻟﻤﯿﺎ، إﻻ أن ﺗﻐﯿﺮ اﻟﻤﻨﺎخ ﻗﺪ ﯾﻜﻮن ﻟﮫ ﺗﺄﺛﯿﺮ ﻛﺒﯿﺮ ﻋﻠﯿﮭﺎ, ﻣﻦ ﺣﯿﺚ أﻧﮫ ﯾﻐﯿﺮ اﻟﻨﻈﺎم اﻟﺒﯿﺌﻲ، وﯾﻀﻌﻒ ﺻﺤﺔ اﻷﺳﻤﺎك، وﯾﺰﯾﺪ ﻣﻦ ﺧﻄﺮ اﻹﺻﺎﺑﺔ ﺑﺎﻷﻣﺮاض. وﻧﺘﯿﺠﺔ ﻻرﺗﻔﺎع درﺟﺎت اﻟﺤﺮارة وﺗﻐﯿﺮات درﺟﺔ اﻟﺤﻤﻮﺿﺔ ﻗﺪ ﺗﻨﺘﺸﺮ اﻟﺒﻜﺘﯿﺮﯾﺎ اﻟﻤﻘﺎوﻣﺔ ﻟﻤﻀﺎدات اﻟﻤﯿﻜﺮوﺑﺎت، ﻣﺜﻞ اﻟﺰاﺋﻔﺔ اﻟﺰﻧﺠﺎرﯾﺔ aeruginosa) (P. واﻹﺷﺮﯾﻜﯿﺔ اﻟﻘﻮﻟﻮﻧﯿﺔ coli) (E.، ﻣﻤﺎ ﯾﻌﺮض اﻟﺼﺤﺔ اﻟﻌﺎﻣﺔ وﺳﻼﻣﺔ اﻷﻏﺬﯾﺔ ﻟﻠﺨﻄﺮ وﻟﺬا ﻓﻘﺪ ﺗﻢ ﺟﻤﻊ ۳۲۸ ﻋﯿﻨﺔ ﻣﻦ أﺳﻤﺎك اﻟﺒﻠﻄﻲ اﻟﻨﯿﻠﻰ niloticus) (Oreochromis ﻣﻦ ﺑﻌﺾ اﻟﻤﺰارع اﻟﺴﻤﻜﯿﺔ اﻟﻤﺼﺮﯾﺔ وﺗﻢ ﺗﺼﻨﯿﻔﮭﺎ ﺣﺴﺐ اﻟﺘﻐﯿﺮات اﻟﺒﯿﺌﯿﺔ واﻟﻤﻮﺳﻤﯿﺔ. و ﺑﺎﺳﺘﺨﺪام اﻟﺘﻘﻨﯿﺎت اﻟﺠﺰﯾﺌﯿﺔ ﺗﻢ ﻋﺰل اﻟﻤﯿﻜﺮوﺑﺎت ﻣﻦ اﻟﻨﻮع P. aeruginosa وcoli .E. ﺣﯿﺚ ﻛﺎﻧﺖ ﻣﯿﻜﺮوﺑﺎت P.aeruginosa ﻣﻨﺘﺸﺮة ﺑﺸﻜﻞ ﻛﺒﯿﺮ (۱۲ ۹٥٫ ٪) ﻓﻲ ﺟﻤﯿﻊ ﻣﺠﻤﻮﻋﺎت اﻷﺳﻤﺎك اﻟﻤﻔﺤﻮﺻﺔ، ووﺻﻠﺖ إﻟﻰ ذروﺗﮭﺎ ﻓﻲ اﻟﺼﯿﻒ، وﺳﺠﻠﺖ اﻟﺪراﺳﺔ زﯾﺎدة ﻓﻰ ﻣﻌﺪل ﺟﯿﻨﺎت اﻟﻀﺮاوة اﻟﺨﺎﺻﺔ ﺑﺎﻟﻤﯿﻜﺮوب، ﻣﺜﻞ exoS، وToxA، وoprL، وphzM، ﻣﻊ ارﺗﻔﺎع درﺟﺔ اﻟﺤﺮارة. و ﺑﺎﺳﺘﺨﺪام ﺗﻘﻨﯿﺔ ﺗﻔﺎﻋﻞ اﻟﺒﻠﻤﺮة اﻟﻤﺘﺴﻠﺴﻞ ﻟﻠﻜﺸﻒ ﻋﻦ ﺗﻮاﺟﺪ اﻟﺠﯿﻨﺎت اﻟﺨﺎﺻﺔ ﺑﻤﻘﺎوﻣﺔ اﻟﺒﯿﺘﺎ ﻻﻛﺘﺎﻣﺎز واﻟﻜﺎرﺑﺎﺑﯿﻨﯿﻤﺎز, وﺟﺪ أن blaTEM و blaOXA-48 ﻛﺎﻧﺎ أﻛﺜﺮ ﺷﯿﻮﻋًﺎ ﻓﻲ ﻓﺼﻞ اﻟﺼﯿﻒ، و ﺑﺎﺟﺮاء ﺗﺤﻠﯿﻞ اﻟﻨﺸﻮء واﻟﺘﻄﻮر ﻟﻠﺠﯿﻦ oprL وﺟﺪ أن ھﻨﺎك ﺗﺸﺎﺑﺔ ﺑﯿﻦ ﻋﺰﻻت aeruginosa P.اﻟﻤﻌﺰوﻟﺔ ﻣﻦ ﻋﯿﻨﺎت اﻷﺳﻤﺎك و اﻟﺴﻼﻻت اﻟﻤﺮﺗﺒﻄﺔ ﺑﺎﻟﺒﺸﺮ اﻟﺘﻰ ﺗﻮﺟﺪ ﻋﻠﻰ ﺑﻨﻚ اﻟﺠﯿﻨﺎت. وﻋﻠﻰ اﻟﺠﺎﻧﺐ اﻷﺧﺮ ﻓﻘﺪ ﻛﺎن ﻣﻌﺪل اﻧﺘﺸﺎرﻣﯿﻜﺮوب اﻹﺷﺮﯾﻜﯿﺔ اﻟﻘﻮﻟﻮﻧﯿﺔ ﻣﺮﺗﻔﻌًﺎ ﺑﺸﻜﻞ ﻣﻠﺤﻮظ ( ٨ ٦ ,۹۲ ٪). وأظﮭﺮ ارﺗﺒﺎطًﺎ ﻗﻮﯾًﺎ ﺑﺎرﺗﻔﺎع درﺟﺎت ﺣﺮارة اﻟﻤﯿﺎه. ﻛﻤﺎ ﺗﻢ اﻛﺘﺸﺎف ﻣﯿﻜﺮوب اﻹﺷﺮﯾﻜﯿﺔ اﻟﻘﻮﻟﻮﻧﯿﺔ اﻟﻤﺴﺒﺒﺔ <br/><br/><br/>ﻟﻺﺳﮭﺎل ﻓﻲ) ۸۲٫۱ ٪ (ﻣﻦ اﻟﻌﯿﻨﺎت، وﺗﻢ ﺗﺤﺪﯾﺪ اﻹﺷﺮﯾﻜﯿﺔ اﻟﻘﻮﻟﻮﻧﯿﺔ اﻟﻤﻌﻮﯾﺔ (ETEC) ﻋﻠﻰ أﻧﮭﺎ اﻟﻨﻤﻂ اﻟﻤﺮﺿﻲ اﻟﺴﺎﺋﺪ ( ۸٤, ٦ ۸ ٪.( وﻛﺸﻔﺖ اﻟﺪراﺳﺔ ﻋﻦ ﺗﻮاﺟﺪ ﺳﻼﻻت ھﺠﯿﻨﺔ ﺗﺤﻤﻞ ﺟﯿﻨﺎت ﺿﺮاوة ﻣﺘﻌﺪدة، ﻛﻤﺎ اﻧﺘﺸﺮت ﺟﯿﻨﺎت اﻟﻤﻘﺎوﻣﺔ ﻣﺜﻞ blaTEM ، وblaCTX-M ، و blaOXA-48 ﻓﻲ اﻟﻤﯿﻜﺮوب ﻓﻰ اﻷﺷﮭﺮ اﻷﻛﺜﺮ دﻓﺌًﺎ ﻣﻦ اﻟﻌﺎم. وﻗﺪ ﺧﻠﺼﺖ اﻟﺪراﺳﺔ اﻟﻰ أن اﻟﻀﻐﻮط اﻟﺒﯿﺌﯿﺔ، ﺑﻤﺎ ﻓﻲ ذﻟﻚ ﻣﻦ ﺗﻐﯿﺮات ﻓﻰ درﺟﺔ اﻟﺤﺮارة ودرﺟﺔ اﻟﺤﻤﻮﺿﺔ، ﻗﺪ ﺗﺴﺎھﻢ ﻓﻲ زﯾﺎدة اﻟﻤﻘﺎوﻣﺔ واﻟﻀﺮاوة ﻟﻠﻤﺴﺒﺒﺎت اﻟﻤﺮﺿﯿﺔ اﻟﻤﻌﺰوﻟﺔ ﻣﻦ ﻋﯿﻨﺎت اﻷﺳﻤﺎك. و ﺑﺎﻟﺘﺎﻟﻰ ﻓﺎن ارﺗﻔﺎع درﺟﺎت اﻟﺤﺮارة واﺧﺘﻼل ﺗﻮازن اﻷس اﻟﮭﯿﺪروﺟﯿﻨﻲ، اﻟﻨﺎﺟﻢ ﻋﻠﻰ اﻷرﺟﺢ ﻋﻦ ﺗﻐﯿﺮ اﻟﻤﻨﺎخ، ﻗﺪ ﯾﺴﺎھﻢ ﻓﻰ زﯾﺎدة ﺿﺮاوة اﻟﻤﯿﻜﺮوﺑﺎت وﻣﻘﺎوﻣﺘﮭﺎ ﻟﻤﻀﺎدات اﻟﻤﯿﻜﺮوﺑﺎت ﻓﻲ ﺗﺮﺑﯿﺔ اﻷﺣﯿﺎء اﻟﻤﺎﺋﯿﺔ. ﻟﺬا ﻓﻘﺪ ﺳﻠﻄﺖ ھﺬه اﻟﺪراﺳﺔ اﻟﻀﻮء ﻋﻠﻰ ﺿﺮورة اﻟﻤﺮاﻗﺒﺔ اﻟﺮوﺗﯿﻨﯿﺔ وﺗﺤﺴﯿﻦ اﻟﺼﺮف اﻟﺼﺤﻲ، ﻟﻠﺘﺨﻔﯿﻒ ﻣﻦ ھﺬه اﻟﻤﺨﺎطﺮ وﺿﻤﺎن ﺗﺮﺑﯿﺔ اﻷﺣﯿﺎء اﻟﻤﺎﺋﯿﺔ اﻟﻤﺴﺘﺪاﻣﺔ وﺳﻼﻣﺔ اﻟﺼﺤﺔ اﻟﻌﺎﻣﺔ. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Veterinary Science |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | العلوم البيطرية |
| 653 #0 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Climate change |
| -- | aquaculture |
| -- | P. aeruginosa |
| -- | E. coli, |
| -- | virulence genes |
| -- | antimicrobial resistance genes |
| -- | Egypt |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Ahmed Sabry |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalia Anwar Hamza |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zeinab Said Ahmed |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2025 |
| Supervisory body | Maha Ahmed Sabry |
| -- | Dalia Anwar Hamza |
| -- | Zeinab Said Ahmed |
| Universities | Cairo University |
| Faculties | Faculty of Veterinary Medicine |
| Department | Department of Veterinary Medicine Science |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | قاعة الرسائل الجامعية - الدور الاول | قاعة الرسائل الجامعية - الدور الاول | 25.10.2025 | 92247 | Cai01.10.18.M.Sc.2025.Ay.i | 01010110092247000 | 25.10.2025 | 25.10.2025 | Thesis |