Biochemical studies on food fortification with some vitamins and minerals for anemia treatment / (Record no. 176067)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04753namaa22004571i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20251122111329.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251121s2024 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 572 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 572 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.07.04.Ph.D.2024.Ra.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Rania Ahmed Salamma Mahgoub, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Biochemical studies on food fortification with some vitamins and minerals for anemia treatment / |
| Statement of responsibility, etc. | by Rania Ahmed Salamma Mahgoub ; Supervisors Dr. Abdel Kader Moursy Abdel-Samad, Dr.Mohamed Abdel-Moneam Naguib, Dr.Mahmoud Abdel-Haleim Mahmoud, Dr. Hanna Hussein El-Sayed. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات كيميائية حيوية على تزويد الغذاء ببعض الفيتامينات والمعادن لعلاج الانيمياء |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 178 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 156-178. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Iron deficiency anemia (IDA) represents a critical global health concern. This <br/>investigation involves the characterization and evaluation of several <br/>nanoparticle formulations—iron oxide magnetic nanoparticles (IONPs), zinc <br/>oxide nanoparticles (ZnO-NPs), magnesium oxide nanoparticles (MgO-NPs), <br/>and iron folate nanoparticles—as potential treatments for IDA. For the in vivo <br/>study, 110 Sprague-Dawley rats (both female and male) were divided into <br/>seven groups: a normal group, anemic rats, and four groups treated with <br/>various iron formulations. IDA was induced in the rats using an iron-deficient <br/>diet, followed by feeding with different iron compounds until their hemoglobin <br/>levels reached 12 g/dl. The rats were then placed on a normal diet for two <br/>weeks. Biological and hematological parameters were monitored throughout <br/>the treatment. Results indicated that all treated groups showed positive <br/>outcomes, achieving normal values. Notably, iron folate nanoparticles <br/>demonstrated superior bioavailability, with female rats showing 244.23% HRE <br/>ratio/day and 19.89% RBV HRE ratio/day, and male rats showing 155.02% <br/>HRE ratio/day and 16.63% RBV HRE ratio/day, outperforming other treatments. <br/>Histopathological analysis revealed persistent liver tissue damage in anemic <br/>rats treated with FeSO4 and IONPs, though FeMgO-NPs and iron folate <br/>nanoparticles showed better results. The spleen appeared normal across all <br/>repleted groups. These findings suggest that IONPs can enhance iron <br/>bioavailability for IDA treatment, though their efficacy is improved when <br/>combined with other metals to maximize benefits and reduce side effects |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | يمثل فقر الدم الناجم عن نقص الحديد مشكلة صحية عالمية بالغة الاهمية. يتضمن هذا البحث توصيف وتقييم بيولوجي للعديد من تركيبات جزيئات أكسيد الحديد النانوية في علاجات فقر الدم الناجم عن نقص الحديد. اشارت النتائج الى ان جميع المجموعات المعالجة حققت قيما طبيعية. والجدير بالذكر ان جزيئات حمض الفوليك النانوية أظهرت توافرا حيويا متفوقا. تشير هذه النتائج الى ان جزيئات أكسيد الحديد النانوية يمكن ان تعزز التوافر الحيوي للحديد لعلاج فقر الدم الناجم عن نقص الحديد وتتحسن فعاليتها عند دمجها مع معادن نانوية وحمض الفوليك كفيتامين لتحقيق اقصى قدر من الفوائد وتقليل الاثار الجانبية. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biochemistry |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | الكيمياء الحيوية |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | iron deficiency anemia |
| -- | fortification |
| -- | IONPs |
| -- | nano |
| -- | metals |
| -- | folic acid |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdel Kader Moursy Abdel-Samad |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Abdel- Moneam Naguib |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Abdel-Haleim Mahmoud |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanna Hussein El- Sayed |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Abdel Kader Moursy Abdel-Samad |
| -- | Mohamed Abdel- Moneam Naguib |
| -- | Mahmoud Abdel-Haleim Mahmoud |
| -- | Hanna Hussein El-Sayed |
| Universities | Cairo University |
| Faculties | Faculty of Agriculture |
| Department | Department of Biochemistry |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 21.11.2025 | 92547 | Cai01.07.04.Ph.D.2024.Ra.B | 01010110092547000 | 21.11.2025 | 21.11.2025 | Thesis |