Use of local vancomycin implantation to reduce the risk of surgical site infection in pilon fracture : (Record no. 176346)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06597namaa22004451i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20251224104728.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251130s2025 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 617.158 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 617.158 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.11.25.M.Sc.2025.Ga.U |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Ganesh Moktan Tamang. |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Use of local vancomycin implantation to reduce the risk of surgical site infection in pilon fracture : |
| Remainder of title | randomized control trial / |
| Statement of responsibility, etc. | by Ganesh Moktan Tamang ; Supervision Prof. Dr Abo Bakr Zein Mohamed Said, Dr Ahmed Mohamed Khedr, Dr Ahmed Samir Abd El Monem Bashendy. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الاستخدام الموضعى للفانكوميسين لتقليل احتمالية العدوى بكسور الكاحل المفصلية : |
| Remainder of title | دراسة مقارنة / |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 96 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc)-Cairo University, 2025. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 89-96. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Background <br/>Surgical site infections are infections that develop within 30 days following a surgery (or within 1 year if an implant is left in place) and involve either the incision or deeper tissues at the surgery site(68). Surgical site infections (SSIs) continue to be a major complication after orthopedic surgeries, especially in complex fractures such as pilon fractures that affect the distal tibia and where there is extensive soft tissue injury. Vancomycin, a broad-spectrum antibiotic, has proven effective in preventing SSIs when administered systemically. However, applying vancomycin locally could offer more precise delivery, minimizing systemic side effects and enhancing its antimicrobial action at the surgical site(10).<br/>Objective<br/> This study investigates the effectiveness of local vancomycin application in reducing the incidence of surgical site infections in patients undergoing surgery for pilon fractures.<br/>Methods<br/> In this randomized controlled trial, 60 patients undergoing ORIF for pilon fractures were randomly assigned to two groups: Group A (n=30), where patients will be given local vancomycin implantation at the fracture site, and Group B (n=30), where patients will not be given local vancomycin . Both groups were monitored for the occurrence of SSIs within 6 months post-surgery, and the incidence, type, and severity of infections were recorded. Secondary outcomes included wound healing time, need for additional surgical interventions, and adverse events related to vancomycin implantation.<br/>Results<br/>Out of 60 patients, 10 (16.7%)patients developed surgical site infections (SSIs), with 5 (16.7%) patients from the vancomycin group and 5 (16.7%) patients from the non-vancomycin group.Thus,there is no statistical significant difference in infection rate between both vancomycin users and non users. (P value =1.000).<br/>Conclusion<br/>Local vancomycin implantation has no role for reducing SSIs in pilon fracture surgeries. Further studies are needed to optimize implantation techniques and assess long-term effects, including the risk of antibiotic resistance. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | كسور بيلون هي كسور معقدة داخل المفصل ناتجة عن قوى الضغط المحوري عالية الطاقة المطبقة على الساق. ترتبط هذه الكسور عادةً بتفتت كبير في العظام وتلف الأنسجة الرخوة المحيطة. يتضمن علاج كسور العمود الفقري الجراحة في المقام الأول، وعلى الرغم من تحسن التقنيات الجراحية، إلا أنها تظل إجراءً صعبًا يؤدي غالبًا إلى مضاعفات، أحدها هو التهابات الموقع الجراحي.<br/>شملت هذه الدراسة 60 مريضًا تزيد أعمارهم عن 18 عامًا مصابين بكسور في العمود الفقري وكان من المقرر تثبيتهم بالصفيحة والمسمار. تم تقسيم المرضى عشوائيًا إلى مجموعتين: المجموعة أ (العدد = 30)، حيث تم إجراء زرع الفانكومايسين المحلي في موقع الكسر، والمجموعة ب (العدد = 30)، حيث لم يتم إعطاء الفانكومايسين المحلي.<br/>كان متوسط العمر 40.07 ± 11.90 سنة ويتراوح من 19 إلى 63 سنة وكان هناك 46 (76.7٪) ذكور و 14 (23.3٪) إناث. من بين 60 مريضًا، أصيب 10 (16.7%) من المرضى بالتهابات الموقع الجراحي (SSIs)، مع 5 (16.7%) مرضى من مجموعة الفانكومايسين و5 (16.7%) مرضى من المجموعة غير الفانكومايسين. كانت المكورات العنقودية هي الكائن الحي المعزول في جميع المرضى.<br/>خلصت دراستنا إلى أن الفانكومايسين الموضعي لم يكن له تأثير كبير على حدوث مثبطات مباحث أمن الدولة لدى المرضى الذين يعانون من كسور العمود الفقري بالمقارنة مع المجموعة الضابطة، بعد 6 أشهر من الجراحة.<br/>بناءً على النتائج التي توصلنا إليها، نوصي بإجراء بحث إضافي بأحجام عينات أكبر وفترات متابعة ممتدة للتحقق من هذه النتائج والتحقيق في الاختلافات المحتملة في فعالية الفانكومايسين الموضعي عبر الحالات السريرية المختلفة. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ankle Fractures |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | كسور الكاحل |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pilon fracture |
| -- | surgical site infection |
| -- | vancomycin |
| -- | local implantation |
| -- | infection prevention |
| -- | orthopedic surgery |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abo Bakr Zein Mohamed Said |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mohamed Khedr |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Samir Abd El Monem Bashendy |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2025 |
| Supervisory body | Abo Bakr Zein Mohamed Said |
| -- | Ahmed Mohamed Khedr |
| -- | Ahmed Samir Abd El Monem Bashendy |
| Universities | Cairo University |
| Faculties | Faculty of Medicine |
| Department | Department of Orthopedic Surgery |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 30.11.2025 | 92637 | Cai01.11.25.M.Sc.2025.Ga.U | 01010110092637000 | 30.11.2025 | 30.11.2025 | Thesis |