Study of probiotic bacteria isolated from human milk / (Record no. 176985)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05655nam a22004457a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20251223141733.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251223s2025 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.664 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 612.664 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.12.05.M.Sc.2025.Am.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Amany Abdel Mawla Mostafa Eltaliawy, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Study of probiotic bacteria isolated from human milk / |
| Statement of responsibility, etc. | by Amany Abdel Mawla Mostafa Eltaliawy ; Supervisors Prof. Dr. Zeinat kamel Mohamed, Prof.Dr. Mary Sobhy Khalil, Prof. Dr. Nayra Shaker Mehanna. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | : دراسة بكتيريا البروبيوتك المعزولة من لبن الأم |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 98 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | hesis (M.Sc)-Cairo University, 2025. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 84-98. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | The objective of this study is to isolate probiotic bacteria from human <br/>breast milk and test their health benefits such as cholesterol reduction and <br/>human DNA protection. <br/>Potential probiotic bacteria were isolated from human milk. The <br/>probiotic properties were tested namely their ability to survive acidic pH, <br/>tolerate bile salts and antimicrobial activities. Serum cholesterol reduction <br/>ability and cytoprotective effect on Hep-2 cells were studied. <br/>Results: A total of 48 different isolates were purified from 12 breast <br/>milk samples. They all tolerated bile salts while 81% were proved to be resistant <br/>to acidic pH and had antimicrobial effects against different pathogens. Three <br/>isolates showed high ability to reduce cholesterol from 19.4-22.6%. This <br/>percentage of cholesterol reduction was improved in presence of bile salt to be <br/>48.7-54.7%. Four isolates were proved for a protective effect against the H2O2 <br/>cytotoxicity by decreasing tail moment up to 2.8 and 15.6% DNA concentration <br/>in the tail of the examined cells. Phenotypic characteristics and 16S rDNA <br/>sequence analyses were used to identify the promising isolates as Pediococcus <br/>pentosaceus, Enterococcus durans and Enterococcus faecium strains. <br/>Conclusion: Probiotic strains isolated from human milk in the study <br/>had a dual beneficial role; human health benefit as well as cytoprotective <br/>activities. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | من هذه الدراسة هو عزل بكتيريا البروبيوتيك من لبن الأم واختبار فوائدها الصحية مثل خفض الكوليسترول وحماية الحمض النووي للخلايا البشرية. <br/>تم عزل عينات بكتيريا البروبيوتيك المحتملة من لبن الأمهات. و تم اختبار خصائصها البروبيوتيك وهي قدرتها على البقاء حية في درجة الحموضة المنخفضة، وتحمل الأملاح الصفراوية و امتلاكها الأنشطة المضادة للميكروبات و حساسيتها للمضادات الحيوية. ثم تمت دراسة قدرة بعض العزلات على خفض نسبة الكوليسترول في الدم والتأثير الوقائي للخلايا على خلايا Hep-2 ضد التسمم الخلوي بـ H2O2.<br/>النتائج: تم تنقية 48 عزلة مختلفة من 12 عينة من لبن الأمهات. لقد تحملوا جميعًا الأملاح الصفراوية بينما ثبت أن 81٪ منهم مقاومون لدرجة الحموضة المنخفضة و لديهم حساسية من المضادات الحيوية وكان لهم تأثيرات مضادة للميكروبات ضد مسببات الأمراض المختلفة. و أظهرت ثلاث عزلات قدرة عالية على خفض نسبة الكوليسترول من 19.4-22.6%، وقد تحسنت هذه النسبة لخفض الكوليسترول بوجود الملح الصفراوي لتصل إلى 48.7-54.7%. و تم إثبات تأثير أربع عزلات ضد التسمم الخلوي بـ H2O2 من خلال تقليل عزم الذيل إلى 2.8 و15.6% من تركيز الحمض النووي في ذيل الخلايا التى تم فحصها. ثم تم استخدام الخصائص المظهرية وتحليل تسلسل الحمض النووي الريبي لتحديد العزلات الواعدة و هى سلالات Pediococcus pentosaceus وEnterococcus durans وEnterococcus faecium .<br/>الاستنتاج: كان لسلالات البروبيوتيك المعزولة من لبن الأم في الدراسة دور مفيد مزدوج حيث أن له فائدة صحية وكذلك أنشطة للحماية الخلوية. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Human Milk |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | لبن الأم |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Probiotic bacteria |
| -- | human milk |
| -- | breast milk |
| -- | cholesterol reduction |
| -- | cytotoxicity |
| -- | comet assay |
| -- | cytoprotective |
| -- | Enterococcus |
| -- | durans |
| -- | faecium |
| -- | البكتيريا بروبيوتيك |
| -- | لبن الأم |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zeinat kamel Mohamed |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mary Sobhy Khalil |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nayra Shaker Mehanna |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2025 |
| Supervisory body | Zeinat kamel Mohamed |
| -- | Mary Sobhy Khalil |
| -- | Nayra Shaker Mehanna |
| Universities | Cairo University |
| Faculties | Faculty of Science |
| Department | Department of Botany and Microbiology |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 23.12.2025 | 92901 | Cai01.12.05.M.Sc.2025.Am.S | 01010110092901000 | 23.12.2025 | 23.12.2025 | Thesis |