Challenges of using proteomics mass spectrometry for bladder cancer prognostic biomarkers / (Record no. 177702)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 04161namaa22004451i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20260121111137.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 260114s2024 |||a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.99462 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 616.99462 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.12.02.M.Sc.2024.Ma.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Margrit Saad Nessim Gendi, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Challenges of using proteomics mass spectrometry for bladder cancer prognostic biomarkers / |
| Statement of responsibility, etc. | by Margrit Saad Nessim Gendi ; Supervisors Prof.Dr. Ahmed Elsherif, Dr.Heba Mohamed Kamal, Dr. Ola Sayeed Ahmed. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | استخدام البروتيوميات و قياس الكتلة الطيفي كتحديات للتشخيص الحيوي لسرطان المثانة |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 91 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 70-90. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Aim To discover biomarkers for bladder cancer in specimens of blood <br/>and tissue. Using proteomics platforms, such as high throughput mass <br/>spectrometry. Several proteins in the tissue and plasma were assessed <br/>using bioinformatics analysis of the data. Subject our study consisted <br/>of 40 specimens divided into three groups: BCT (15 fresh-frozen <br/>tissue samples), BCP (15 plasma samples from bladder cancer <br/>patients), and CTRL (10 plasma samples from healthy individuals). <br/>Results: Six candidate biomarkers were detected in BC patients: <br/>gelsolin, haptoglobin, SERPINA1, A2M, and delta and beta globulin <br/>proteins in both tissue and plasma specimens. Conclusion: In plasma <br/>cancer Egyptian patients: A2M and SERPINA1 can be used as a <br/>potential biomarkers for bladder cancer. While GSN and HP <br/>biomarkers harbored for tissue bladder cancer samples. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | الهدف اكتشاف المؤشرات الحيوية لسرطان المثانة في عينات الدم والأنسجة. استخدام منصات البروتينات، مثل قياس الطيف الكتلي عالي الإنتاجية. تم تقييم العديد من البروتينات في الأنسجة والبلازما باستخدام تحليل المعلوماتية الحيوية للبيانات. <br/>يتكون موضوع دراستنا من 40 عينة مقسمة إلى ثلاث مجموعات:ادوات<br/> ، BCP ، (15 عينة بلازما من مرضى سرطان المثانة)BCT (15 عينة أنسجة مجمدة طازجة)<br/> CTRL (10 عينات بلازما من أفراد أصحاء)و <br/>النتائج: تم الكشف عن ستة مؤشرات حيوية مرشحة في مرضى كولومبيا البريطانية: جلسولين، هابتوغلوبين، SERPINA1، A2M، وبروتينات دلتا وبيتا الجلوبيولين في عينات الأنسجة والبلازما<br/>الاستنتاج:في مرضى سرطان المثانه في البلازما للمصريين: يمكن استخدام كمؤشرات حيوية محتملة لسرطان المثانه .A2Mو SERPINA1 <br/>كانت المؤشرات الحيوية لعينات سرطان المثانة في الأنسجة.HP و GSNبينما |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bladder Cancer |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | سرطان المثانة |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Proteomic biomarker |
| -- | bladder cancer |
| -- | bioinformatics analysis |
| -- | mass spectrometry |
| -- | tissue |
| -- | plasma |
| -- | سرطان المثانة |
| -- | العلامات الحيوية البروتينية |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Elsherif |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Mohamed Kamal |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ola Sayeed Ahmed |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2024 |
| Supervisory body | Ahmed Elsherif |
| -- | Heba Mohamed Kamal |
| -- | Ola Sayeed Ahmed |
| Universities | Cairo University |
| Faculties | Faculty of Science |
| Department | Department of Chemistry |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 14.01.2026 | 93142 | Cai01.12.02.M.Sc.2024.Ma.C | 01010110093142000 | 14.01.2026 | 14.01.2026 | Thesis |