Effect of low level laser therpay (LLLT) versus calcium hydroxide intra-canal medication on post-operative pain and total amount of substance p and il-8 in periapical fluids in patients with symptomatic apical periodontitis : (Record no. 177991)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 07639namaa22004451i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20260124144904.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 260124s2024 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 617.634 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 617.634 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.09.09.Ph.D.2024.Ra.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Radhwa Refaat Otaify, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of low level laser therpay (LLLT) versus calcium hydroxide intra-canal medication on post-operative pain and total amount of substance p and il-8 in periapical fluids in patients with symptomatic apical periodontitis : |
| Remainder of title | a randomized clinical trial / |
| Statement of responsibility, etc. | by Radhwa Refaat Otaify ; Supervisors Prof. Dr. Angie Galal Ghoneim, Prof. Dr. Olfat Gamil Shaker, Dr. Sarah Samir Abouelenien. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير العلاج بالليزر منخفض المستوى مقابل استخدام هيدروكسيد الكالسيوم كدواء داخل القناة الجذرية على ألم ما بعد الجراحة والكمية الإجمالية للمادة P وIL-8 في السوائل حول الذروة في المرضى الذين يعانون من التهاب دواعم الأسنان العرضي : |
| Remainder of title | تجربة سريرية عشوائية |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 155 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2024. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 151-137. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Aim: To compare the effect of using low level laser therapy versus Calcium Hydroxide intra-canal medication on incidence and intensity of post-operative pain, intensity of post-operative percussion pain as well as total amount of substance P and IL-8 in periapical fluids 1-week post instrumentation in patients with symptomatic apical periodontitis.<br/>Methodology: Forty-eight patients diagnosed with symptomatic apical periodontitis in single canalled teeth were recruited to participate in the study. Subjects were divided into two groups by random allocation. Root canal treatment was performed in two visits. At the first visit, preoperative pain and preoperative percussion pain were recorded. Chemico-mechanical preparation was performed then post-instrumentation periapical sample (PS-1) was collected. For the control group, the canal was filled with Calcium Hydroxide, while the intervention group received low level laser therapy. Patients were requested to record the incidence and intensity of pain on modified VAS scale at 6,12, 24 and 48 hours postoperatively. In the recall visit after 1 week, percussion pain was re-assessed and a second periapical sample (PS-2) was taken. Quantification of substance P and IL-8 was done using ELISA test. <br/><br/>Results: There was no significant difference between both groups in pain intensity and incidence postoperatively at 6, 12,24 and 48 hours as well as in percussion pain intensity and incidence at 1 week postoperatively (p > 0.05). However, LLLT showed significantly higher post-operative levels of IL-8 and substance P as compared to Calcium Hydroxide group (p = 0.003, p = 0.001 respectively). Meanwhile, the reduction of IL-8 and substance P levels showed no significant difference between both groups (p = 0.123, p = 0.385 respectively).<br/><br/>Conclusion: Within the limitations of this study, it was concluded that LLLT could be used alternatively with the same effectiveness of 1-week Calcium Hydroxide intracanal medication in treating teeth with symptomatic apical periodontitis as regarding the intensity and incidence of post-operative pain and percussion pain. Both groups showed comparable periapical tissue response with similar reduction of substance P and IL-8 levels in periapical fluids.<br/>Clinical relevance: Teeth with symptomatic apical periodontitis could be successfully treated in single visit using LLLT without the need of Calcium Hydroxide intracanal medication. This could help avoiding the hazards and complications of multiple-visits treatment. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | هدف البحث:<br/>الهدف من هذه الدراسة هو مقارنة تأثير استخدام العلاج بالليزر منخفض المستوى مقابل دواء هيدروكسيد الكالسيوم داخل القناة على حدوث وشدة الألم بعد العملية الجراحية، وشدة آلام القرع بعد العملية الجراحية، وكذلك الكمية الإجمالية للمادة P وIL-8 في السوائل المحيطة بالذروة بعد أسبوع واحد من استخدام الأجهزة. في المرضى الذين يعانون من أعراض التهاب اللثة القمي<br/>طريقة البحث:<br/> تم انضمام 48 مريضا تم تشخيص إصابتهم بالتهاب اللثة القمي في أسنان ذات قناة واحدة للمشاركة في الدراسة. تم تقسيم المواضيع إلى مجموعتين عن طريق التخصيص العشوائي. تم إجراء علاج قناة الجذر في زيارتين. في الزيارة الأولى، تم تسجيل الألم قبل الجراحة وألم القرع قبل الجراحة. تم إجراء التحضير الكيميائي والميكانيكي ثم تم جمع العينة المحيطة بالأجهزة (PS-1). بالنسبة للمجموعة الضابطة، تم ملء القناة بهيدروكسيد الكالسيوم، بينما تلقت المجموعة الأخرى العلاج بالليزر منخفض المستوى. طُلب من المرضى تسجيل حدوث وشدة الألم على مقياس خدمات القيمة المضافة المعدل عند 6،12، 24 و48 ساعة. في زيارة الاستدعاء بعد أسبوع واحد، تمت إعادة تقييم ألم الإيقاع وتم أخذ عينة محيطة ثانية (PS-2). تم إجراء القياس الكمي للمادة P و IL-8 باستخدام مجموعة ELISA.<br/><br/>النتائج:<br/>لم يكن هناك فرق كبير بين المجموعتين في شدة الألم وحدوثه بعد العمل الجراحي عند 6 و12 و24 و48 ساعة وكذلك في شدة ألم القرع وحدوثه بعد أسبوع واحد بعد العمل الجراحي (P > 0.05). ومع ذلك، أظهر LLLT مستويات IL-8 والمادة أعلى بكثير بعد العملية الجراحية مقارنة بمجموعة هيدروكسيد الكالسيوم (ع = 0.003، ع = 0.001 على التوالي). وفي الوقت نفسه، أظهر انخفاض مستويات IL-8 والمادة P عدم وجود فرق كبير بين المجموعتين (ع = 0.123، ع = 0.385 على التوالي). |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Endodontics |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | علاج الجذور |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | LLLT |
| -- | Biomodulation |
| -- | Calcium Hydroxie |
| -- | Post-operative Pain |
| -- | Post-operative Percussion Pain |
| -- | IL-8 |
| -- | Substance P |
| -- | Biomarkers |
| -- | Symptomatic Apical Periodontitis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Angie Galal Ghoneim |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat Gamil Shaker |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sarah Samir Abouelenien |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2025 |
| Supervisory body | Angie Galal Ghoneim |
| -- | Olfat Gamil Shaker |
| -- | Sarah Samir Abouelenien |
| Universities | Cairo University |
| Faculties | Faculty of Dentistry |
| Department | Department of Endodontics |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 24.01.2026 | 93227 | Cai01.09.09.Ph.D.2024.Ma.C | 01010110093227000 | 24.01.2026 | 24.01.2026 | Thesis |