Survey of pediatric renal stone disease in the nephrology outpatient clinic of Cairo university children hospitals / (Record no. 178806)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 07811namaa22004451i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20260302195020.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 260302s2025 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 618.92 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 618.92 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.11.28.M.Sc.2025.Re.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Remeen Sabry Hassan Mohamed, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Survey of pediatric renal stone disease in the nephrology outpatient clinic of Cairo university children hospitals / |
| Statement of responsibility, etc. | by Remeen Sabry Hassan Mohamed ; Supervisors Prof. Dr. Amal Mostafa Hagras, Prof. Dr. Samar Mohamed Sabry, Prof. Dr. Doaa Mohamed Salah. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة استقصائية حول مرض حصوات الكلي في الأطفال المترددين علي العيادات الخارجيه لوحده الكلي بمستشفيات جامعة القاهرة |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 122 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc)-Cairo University, 2025. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 107-122. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Background: <br/>Kidney stones represent a significant health issue in children, with a globally increasing <br/>incidence. The rising incidence is attributed to various factors such as increased sensitivity of <br/>radiological imaging, systematic screening for metabolic risk factors, changes in nutrition <br/>patterns, consanguinity and rise in childhood obesity. <br/>Aim of the Study: <br/>This study aims to study renal stone disease in Egyptian children attending the Pediatric <br/>Nephrology Outpatient Clinic of Cairo University Children's Hospital (CUCH). It also seeks <br/>to document the epidemiological characteristics of the disease in Egyptian children and to <br/>determine the possible causes, management, and short-term outcomes. <br/>Methods: <br/>A retrospective descriptive study of 128 patients (<13 years) with kidney stones <br/>attending Cairo University Children’s Hospital (2015–2019). Data were collected from medical <br/>records, focusing on demographics, clinical presentation, imaging findings, management and <br/>outcome (CKD staging). Laboratory investigations included complete blood count, serum <br/>electrolytes (Na, K, Ca, Po4, ALP, Mg), blood gases, BUN and serum creatinine, serum uric <br/>acid,and parathormone ,stone, and urine analysis. Data were analyzed using SPSS version 26, <br/>employing Chi-Square, Fisher's exact test, Mann Whitney U test, and Spearman's correlation <br/>coefficient. <br/>Results: <br/> The median age of the children ranged from 0.3 to 11.0 years, with a median of 4 <br/>years. The majority were males (74.2%), and 63.3% were from rural areas. Results showed that <br/>60.2% of patients had consanguineous parents, and 50% had a family history of a similar <br/>condition. Renal colic was the most common symptom (25.8%), followed by anuria (14.8%), <br/>and recurrent urinary tract infection (10.9%). The median age of symptom onset was 2 years <br/>(0.1-11 years). Radiological studies revealed that 42 patients (32.8%) had nephrocalcinosis. <br/>Calcium oxalate stones were the most common type (33.6%). The recurrence rate was 19.5%. <br/>Age at diagnosis and age at symptom onset were significantly lower in nephrocalcinosis cases <br/>compared to kidney stone cases. Hypercalciuria was significantly more common in patients <br/>with stone recurrence. Passage of gravels or small stones (P value=0.001) was significantly <br/>higher in patients with uric acid stones. All patient with cystine stone were sibling of <br/>consanguineous marriage. GFR was significantly lower in obstructive group than non-<br/>obstructive (P value=0.001). There was a negative correlation between Ca/ creatinine ratio and <br/>GFR (r = -0.426, P value =0.001). <br/>Conclusion: <br/> Calcium oxalate dominates pediatric stones in Egypt, nephrocalcinosis is a prevalent <br/>condition with consanguinity and rural residence as key risk factors. Obstructive stones and <br/>recurrence correlate with renal impairment. Tailored prevention strategies and multicenter <br/>studies are recommended. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | المقدمة:<br/>مرض حصوات الكلى هو اضطراب أيضي جهازي يرتبط بزيادة مخاطر الإصابة بأمراض القلب والأوعية الدموية، وأمراض الكلى المزمنة لدى البالغين، وكذلك بزيادة خطر حدوث الكسور لدى الأطفال والبالغين.<br/>تتكوَّن حصوات الكلى نتيجة زيادة تركيز المواد الذائبة المعنية، وتُسهم عوامل متعددة في تجمّع هذه المواد والتصاقها بخلايا الأنابيب الكلوية، مثل درجة حموضة البول، عدم كفاءة المثبطات الطبيعية للتبلور، ركود البول، بالإضافة إلى تلف الأنابيب الكلوية .(<br/>في الآونة الأخيرة، لوحظ ارتفاع تدريجي في معدل حدوث حصوات الجهاز البولي لدى الأطفال، خاصة في الدول المتقدمة، حيث أُبلغ عن زيادة في حالات حصى الكلى بمقدار خمسة أضعاف في كل من أمريكا الشمالية وتركيا.<br/>تُعد منطقة الحزام الحجري الأفروآسيوي، من المناطق ذات المعدلات العالية من الإصابة والانتشارلمرض حصوات الكلى، وتمتد من السودان ومصر في إفريقيا إلى المملكة العربية السعودية، وإيران، وتركيا، وباكستان، والهند في آسيا.<br/>يمكن تفسير هذا الارتفاع في معدل الإصابة بعدة عوامل، منها: زيادة دقة التصوير الشعاعي، الفحص المنهجي لعوامل الخطر الأيضية، التغيرات في النمط الغذائي، زواج الأقارب، وارتفاع معدلات السمنة لدى الأطفال. كما يُعتقد أن الاحتباس الحراري وتغير المناخ يسهمان أيضًا في ذلك. معظم الحالات تكون مرتبطة باضطرابات أيضية .<br/>تعتبر حصوات أوكسالات الكالسيوم هي الأكثر شيوعًا لدى الأطفال، حيث تشكل نسبة 70–80٪ من جميع حصوات الجهاز البولي، بينما تُعد حصوات حمض اليوريك، الستروفيت، والسيستين أقل شيوعا.<br/>الهدف من الدراسة:<br/>هدفت هذه الدراسة إليدراسة مرض حصوات الكلي في الأطفال المترددين علي العيادات الخارجيه لوحده الكلي بمستشفيات جامعة القاهرة ولتوثيق الخصائص الوبائية للمرض لدى الأطفال المصريين وتحديد الأسباب المحتملة والعلاج والنتائج قصيرة المدى. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pediatrics |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | طب الأطفال |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pediatric kidney stones |
| -- | kidney disease |
| -- | children |
| -- | risk factors |
| -- | management |
| -- | Egypt |
| -- | nephrocalcinosis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amal Mostafa Hagras |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samar Mohamed Sabry |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mohamed Salah |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2025 |
| Supervisory body | Amal Mostafa Hagras |
| -- | Samar Mohamed Sabry |
| -- | Doaa Mohamed Salah |
| Universities | Cairo University |
| Faculties | Faculty of Medicine |
| Department | Department of Pediatrics |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 02.03.2026 | 93474 | Cai01.11.28.M.Sc.2025.Re.S | 01010110093474000 | 02.03.2026 | 02.03.2026 | Thesis |