Comparative study of brachytherapy using ring and ovoid applicators in treatment of advanced cervical cancer / (رقم التسجيلة. 179079)
[ عرض عادي ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 07494namaa22004691i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GICUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20260412120410.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 260329s2025 ua a|||frm||| 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GICUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GICUC |
| Modifying agency | EG-GICUC |
| Description conventions | rda |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposit |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.99466 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 616.99466 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.12.04.Ph.D.2025.He.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Hend Mohamed Mahmoud Abd El-Kareem, |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Comparative study of brachytherapy using ring and ovoid applicators in treatment of advanced cervical cancer / |
| Statement of responsibility, etc. | by Hend Mohamed Mahmoud Abd El-Kareem ; Supervisors Prof. Dr. Fadel Mohamed Ali, Prof. Dr. Reem Hassan El-Gebaly, Dr. Reham Salah El-Din Sherif, Prof. Dr. Mohmmad Aboulfetouh Shehata, Dr. Reham Ahmed Abdel Aziz Hassan. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مقارنة للمعالجة الكثبية باستخدام المجسات الحلقية والبيضاوية في سرطان عنق الرحم المتقدم |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 92 pages : |
| Other physical details | illustrations ; |
| Dimensions | 25 cm. + |
| Accompanying material | CD. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D)-Cairo University, 2025. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: pages 80-89. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Introduction: Image-guided brachytherapy became essential to <br/>cervical cancer treatment following chemo-radiotherapy. A variety <br/>of applicators and optimization techniques, including Tandem-Ring <br/>(TR) and Tandem-Ovoid (TO) applicators, are used to apply <br/>brachytherapy. This study aims to dosimetrically compare TR vs. <br/>TO applicators and Ring (R) vs. Ovoid (O) applicators by using <br/>two different optimization techniques. <br/>Materials and Methods: 45 patients were divided into two groups: TR <br/>vs. TO group and R vs. O group; both applicator sets were applied to the <br/>same patients. The prescribed dose was 7.0 Gy/fraction, and the treatment <br/>plans were normalized to HR-CTV. Two different optimization techniques <br/>were applied along the four treatment fractions. The first optimization <br/>technique was a theoretical assumption that was normalized to HR-CTV <br/>and aimed at delivering 7.0 Gy to 90% of the volume of the HR-CTV. <br/>While the second aimed to preserve the organs at risk (OARs) according to <br/>the ICRU 89 dose-volume constraints, taking into account that 90% of HR- <br/>CTV is covered by not less than 90% of the prescribed dose. DVHs were <br/>generated, and dosimetric parameters including left and right of points A <br/>and B, D2.0cc of rectum, bladder, and sigmoid, as well as the dose at <br/>different volumes of HR-CTV and IR-CTV, and total fraction time, were <br/>recorded and compared. <br/>Results: The results demonstrate that using Ovoid applicators either with <br/>or without tandem applicators achieved significantly higher dose at point A, <br/>significantly higher coverage to both HR-CTV and IR-CTV, in addition to <br/>significantly better protection to the mean D2.0cc of the rectum in <br/>both optimization techniques. On the other hand, using ring applicators <br/>either with or without tandem applicators give significantly more protection <br/><br/><br/> <br/><br/>3 <br/><br/> <br/><br/> <br/><br/>to the mean D2.0cc of the bladder, but HR-CTV and IR-CTV have <br/>significantly lower coverage. <br/>Conclusion: Tandem-Ovoid a n d Tandem-Ring applicators are the <br/>most common interchangeable intracavitary gynecological applicators. In <br/>this study, the results demonstrated that both ovoid applicator sets have <br/>the advantages of significantly higher coverage for HR-CTV, IR-<br/>CTV, and more protection for D2.0cc of the rectum. On the contrary, <br/>both ring applicator sets can provide higher protection for D2.0cc of <br/>the bladder, and more comfort to the patients. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | المقدمة: أصبح العلاج الإشعاعي الموضعي الموجه بالصور ضروريًا لعلاج سرطان عنق الرحم بعد العلاج الكيميائي الإشعاعي. يتم استخدام مجموعة متنوعة من أدوات التطبيق و المجسات وتقنيات التحسين بما في ذلك استخدام المجسات Tandem-Ring (TR) و Tandem-Ovoid (TO) لتطبيق العلاج الإشعاعي الموضعي. تهدف هذه الدراسة إلى مقارنة مجسات TR مقابل TO وأدوات تطبيق Ring (R) مقابل Ovoid (O) باستخدام تقنيتين مختلفتين للتحسين.<br/>المواد والطرق: تم تقسيم 45 مريضا إلى مجموعتين. مجموعة TR مقابل TO ومجموعة R مقابل O ، تم تطبيق كلتا المجموعتين على نفس المريض. كانت الجرعة الموصوفة 7 غراي لكل جلسة علاج ، وتم حساب خطط العلاج إلى HR-CTV. يتم تطبيق تقنيتين مختلفتين للتحسين، على طول جلسات المعالجة الأربعة. كانت تقنية التحسين الأولى عبارة عن افتراض نظري يهدف إلى توصيل 7 غراي إلى 90٪ من حجم HR-CTV. <br/>بينما يهدف الثاني إلى الحفاظ على الأعضاء المعرضة للخطر (OARs) وفقًا لقيود الجرعة الموصى عليها من قبل ICRU 89، مع الأخذ في الاعتبار أن 90٪ من HR-CTV يتم تغطيتها بما لا يقل عن 90٪ من الجرعة الموصوفة. <br/>تم استخراج الرسم البياني للجرعة والحجم ، وتم تسجيل متغيرات قياس الجرعات بما في ذلك يسار ويمين النقطتين A وB، وD2cc للمستقيم والمثانة والسيني، بالإضافة إلى الجرعة المسلمة لأحجام مختلفة من HR-CTV وIR-CTV، وإجمالي وقت جلسات المعالجة . وتم المقارنة بينهم.<br/>النتائج: أظهرت النتائج أن استخدام مجسات ال Ovoid سواء مع أو بدون مجسات ال Tandem حقق جرعة أعلى بكثير عند النقطة A، وتغطية أعلى بكثير لكل من HR-CTV وIR-CTV، بالإضافة إلى حماية أفضل بكثير لمتوسط D2cc للمستقيم في كلا تقنيات التحسين. <br/>أما من ناحية أخرى، فإن استخدام مجسات ال Ring ال Ovoid سواء مع أو بدون مجسات ال Tandem يوفر حماية أكبر بكثير لمتوسط D2cc للمثانة، لكن HR-CTV وIR-CTV لهما تغطية أقل بكثير. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issues also as CD. |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Uterine Cervical Neoplasms |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | سرطان عنق الرحم |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Brachytherapy |
| -- | cervical cancer |
| -- | Ovoid applicator |
| -- | Ring applicator |
| -- | براكي ثيرابي |
| -- | سرطان عنق الرحم |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fadel Mohamed Ali |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reem Hassan El-Gebaly |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reham Salah El-Din Sherif |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohmmad Aboulfetouh Shehata |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reham Ahmed Abdel Aziz Hassan |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2025 |
| Supervisory body | Fadel Mohamed Ali |
| -- | Reem Hassan El-Gebaly |
| -- | Reham Salah El-Din Sherif |
| -- | Mohmmad Aboulfetouh Shehata |
| -- | Reham Ahmed Abdel Aziz Hassan |
| Universities | Cairo University |
| Faculties | Faculty of Science |
| Department | Department of Biophysics |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| Reviser Names | Eman Ghareb |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Edition | 21 |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 29.03.2026 | 93607 | Cai01.12.04.Ph.D.2025.He.C | 01010110093607000 | 29.03.2026 | 29.03.2026 | Thesis |