Pharmacological study of the possible antidiabetic action of certain phosphodiesterase inhibitors in experimental rats / (Record no. 51929)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02391cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031256.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150811s2014 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2014.Ah.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Seif Eldin Kamal Abdelwahab Eldeeb |
| 245 10 - TITLE STATEMENT | |
| Title | Pharmacological study of the possible antidiabetic action of certain phosphodiesterase inhibitors in experimental rats / |
| Statement of responsibility, etc. | Ahmed Seif Eldin Kamal Abdelwahab Eldeeb ; Supervised Mostafa Elsayed Elsayed , Nihad Ibrahim Eid |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة دوائية للتأثير المحتمل المضاد لمرض السكرى لبعض مثبطات الفوسفودايستريز فى جرذان التجارب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Seif Eldin Kamal Abdelwahab Eldeeb , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 199 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The study deals with possible antidiabetic action of phosphodiesterase inhibitors in rats. It is composed of in vivo and in vitro studies. In the in vivo study, diabetes was induced by injecting a single dose of streptozotocin (50 mg/kg) then 2 drugs; sildenafil (Sild), vinpocetine (Vinp) were used and gliclazide (Glicl) was used as a reference standard then drugs were administered daily over 2 weeks. The chosen doses were 10 mg/kg for Glicl, 5, 10, 20 mg/kg for Sild, 10, 20, 40 mg / kg for Vinp then glucose, insulin and C - peptide levels were estimated after 2 hours of first dose, 1 week and 2 weeks of drug administration. Also Liver glycogen was measured after 2 weeks. In In vitro study, effect of Vinp, Sild, Glicl was studied individually in concentrations (10, 20, 40, 80 æmol/l) or in combinations for 1 hour on Ý - islets isolated by collagenase digestion technique in glucose (3 or 16.7 mmol/l) and released insulin and cGMP levels were estimated in incubation medium |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Sildenafil |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Streptozotocin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vinpocetine |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mostafa Elsayed Elsayed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nihad Ibrahim Eid , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2014.Ah.P | 01010110066188000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2014.Ah.P | 01020110066188000 | 22.09.2023 | CD - Rom | 66188.CD |