Studies on the microbial synthesis of gold nanoparticles using gamma radiation / (Record no. 54417)

MARC details
000 -LEADER
fixed length control field 03018cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031407.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160112s2015 ua do f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.08.06.M.Sc.2015.Am.S
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Amira Magdy Abdelmonem Mahfouz
245 10 - TITLE STATEMENT
Title Studies on the microbial synthesis of gold nanoparticles using gamma radiation /
Statement of responsibility, etc. Amira Magdy Abdelmonem Mahfouz ; Supervised Magdy Aly Amin , Hala Nour Eldin El Hefnawi , Tamer Mohamed Essam
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسات على التخليق الميكروبى لجسيمات الذهب النانو باستخدام اشعة جاما
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Amira Magdy Abdelmonem Mahfouz ,
Date of publication, distribution, etc. 2015
300 ## - PHYSICAL DESCRIPTION
Extent 137 P. :
Other physical details charts , photographs ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
520 ## - SUMMARY, ETC.
Summary, etc. An eco-friendly, non-toxic and cost-effective protocol for the synthesis of gold nanoparticles (GNPs) using submerged liquid fermentation of the fungus Pleurotus osteratus was established. Treatment of tetrachloro-auric acid (HAuCl4) solution with the free cell filtrate (FCF) of the fungus reduced the HAuCl4 ions and formed stable GNPs. These nanoparticles were characterized by Surface Plasmon Resonance (SPR) band at wavelength 550 nm for GNPs. The media components for the fungal growth were optimized using factorial design. The maximum SPR in UV-Vis spectra was recorded with a medium containing in (%); glucose (1), yeast (0.5), malt extract (0.5) and KNO3 (0.2) and incubation period 8 days, the temperature and pH were kept at 30 oC and 6, respectively. The particles were further characterized by UV/Vis spectroscopy, Transmission electron microscope (TEM), Dynamic light scattering (DLS), Fourier Transform Infrared Spectroscopy (FT-IR) and X-Ray diffraction (XRD). Exposure of fungal strain and FCF after mixing with Au+ to Gamma radiation showed 36 % increase in the SPR band intensity of the synthesized GNPs compared to un-irradiated strain and FCF irradiated before mixing with Au+. Interestingly, the synthesized GNPs exhibited antimicrobial activity against both Gram positive and Gram negative bacteria, as measured by well diffusion assay. No antifungal activity was reported. Moreover, it also showed good anticancer activity against human Breast carcinoma (T47D) cells, Prostate carcinoma (PC3) cells and Hepatocellular carcinoma (HEPG2) cells using Trypan blue exclusion and Sulfo-Rhodamine B assay
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Factorial design
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Pleurotus ostreatus
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Submerged fermentation
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Hala Nour Eldin Elhefnawi ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Magdy Aly Amin ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Tamer Mohamed Essam ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Enas
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.08.06.M.Sc.2015.Am.S 01010110067391000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.08.06.M.Sc.2015.Am.S 01020110067391000 22.09.2023 CD - Rom 67391.CD
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