Studies on the microbial synthesis of gold nanoparticles using gamma radiation / (Record no. 54417)
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                            | 000 -LEADER | |
|---|---|
| fixed length control field | 03018cam a2200349 a 4500 | 
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC | 
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031407.0 | 
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160112s2015 ua do f m 000 0 eng d | 
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC | 
| Language of cataloging | eng | 
| Transcribing agency | EG-GiCUC | 
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng | 
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite | 
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc | 
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.06.M.Sc.2015.Am.S | 
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amira Magdy Abdelmonem Mahfouz | 
| 245 10 - TITLE STATEMENT | |
| Title | Studies on the microbial synthesis of gold nanoparticles using gamma radiation / | 
| Statement of responsibility, etc. | Amira Magdy Abdelmonem Mahfouz ; Supervised Magdy Aly Amin , Hala Nour Eldin El Hefnawi , Tamer Mohamed Essam | 
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات على التخليق الميكروبى لجسيمات الذهب النانو باستخدام اشعة جاما | 
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : | 
| Name of publisher, distributor, etc. | Amira Magdy Abdelmonem Mahfouz , | 
| Date of publication, distribution, etc. | 2015 | 
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 137 P. : | 
| Other physical details | charts , photographs ; | 
| Dimensions | 25cm | 
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology | 
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | An eco-friendly, non-toxic and cost-effective protocol for the synthesis of gold nanoparticles (GNPs) using submerged liquid fermentation of the fungus Pleurotus osteratus was established. Treatment of tetrachloro-auric acid (HAuCl4) solution with the free cell filtrate (FCF) of the fungus reduced the HAuCl4 ions and formed stable GNPs. These nanoparticles were characterized by Surface Plasmon Resonance (SPR) band at wavelength 550 nm for GNPs. The media components for the fungal growth were optimized using factorial design. The maximum SPR in UV-Vis spectra was recorded with a medium containing in (%); glucose (1), yeast (0.5), malt extract (0.5) and KNO3 (0.2) and incubation period 8 days, the temperature and pH were kept at 30 oC and 6, respectively. The particles were further characterized by UV/Vis spectroscopy, Transmission electron microscope (TEM), Dynamic light scattering (DLS), Fourier Transform Infrared Spectroscopy (FT-IR) and X-Ray diffraction (XRD). Exposure of fungal strain and FCF after mixing with Au+ to Gamma radiation showed 36 % increase in the SPR band intensity of the synthesized GNPs compared to un-irradiated strain and FCF irradiated before mixing with Au+. Interestingly, the synthesized GNPs exhibited antimicrobial activity against both Gram positive and Gram negative bacteria, as measured by well diffusion assay. No antifungal activity was reported. Moreover, it also showed good anticancer activity against human Breast carcinoma (T47D) cells, Prostate carcinoma (PC3) cells and Hepatocellular carcinoma (HEPG2) cells using Trypan blue exclusion and Sulfo-Rhodamine B assay | 
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD | 
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Factorial design | 
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pleurotus ostreatus | 
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Submerged fermentation | 
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hala Nour Eldin Elhefnawi , | 
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magdy Aly Amin , | 
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tamer Mohamed Essam , | 
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> | 
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas | 
| Reviser | Cataloger | 
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla | 
| Reviser | Revisor | 
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification | 
| Koha item type | Thesis | 
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number | 
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.06.M.Sc.2015.Am.S | 01010110067391000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.06.M.Sc.2015.Am.S | 01020110067391000 | 22.09.2023 | CD - Rom | 67391.CD |