Somatostatin receptor 2A expression in meningioma histopathological and immunohistochemical study / (رقم التسجيلة. 55454)
[ عرض عادي ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02792cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031438.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160309s2015 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.27.M.Sc.2015.Mi.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mira Maher Sadia |
| 245 10 - TITLE STATEMENT | |
| Title | Somatostatin receptor 2A expression in meningioma histopathological and immunohistochemical study / |
| Statement of responsibility, etc. | Mira Maher Sadia ; Supervised Gina Assaad Assaad Nakhla , Ahmed Abdelmonem Soliman , Shady Elia Anis |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تعبير مستقبل سوماتوستاتين 2أ فى اورام الاغشية السحائية: |
| Remainder of title | دراسة نسيجية مناعية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mira Maher Sadia , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 82 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Meningiomas are the most common among the primary central nervous system tumors. Schwannomas of the craniospinal axis and meningeal hemangiopericytomas are much less frequent tumors, however the distinction between certain histologic subtypes of meningioma and either of them can be challenging in some cases. Somatostatin receptors are highly expressed in meningioma and can be used as a good meningioma immunohistochemical marker. In addition, Somatostatin shows antiproliferative and antiangiogenic effects and can be used as targeted therapy. This study tested the immunohistochemical expression of SSTR2A in 35 cases of meningioma (16 grade I, 14 grade II and 5 grade III), 10 cases of intracranial schwannoma and 10 cases of hemangiopericytoma. The cases were retrieved as routinely processed paraffin blocks from the department of pathology, Kasr Alainy hospital, Cairo university and from a private laboratory. Positive immunostaining for SSTR2A was encountered in 89% of meningiomas, 0% of schwannomas and 0% of hemangiopericytomas (p value < 0.05). In meningiomas, all cases of grade I and grade II showed positive staining and only one out of five cases (20%) of grade III showed positive staining (p < 0.05). SSTR2A is a highly specific marker and can be used in the distinction between meningioma, particularly grade I and II, and schwannoma or hemangiopericytoma. It is also suggested that it can be used as a good prognostic marker for meningioma |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hemangiopericytoma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Meningioma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Schwannoma |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Abdelmonem Soliman , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gina Assaad Assaad Nakhla , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shady Elia Anis , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.27.M.Sc.2015.Mi.S | 01010110068228000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.27.M.Sc.2015.Mi.S | 01020110068228000 | 22.09.2023 | CD - Rom | 68228.CD |