Incidence, Patterns and Effect of Fungal Infections on the Outcome of Patients with Acute Myeloid Leukemia / (Record no. 56741)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03211cam a2200361 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031517.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160531s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.05.Ph.D.2016.Om.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Omar Shawki Farid Arafah |
| 245 10 - TITLE STATEMENT | |
| Title | Incidence, Patterns and Effect of Fungal Infections on the Outcome of Patients with Acute Myeloid Leukemia / |
| Statement of responsibility, etc. | Omar Shawki Farid Arafah ; Supervised Lobna Mohammed Shalaby , Iman Mohamed Zaki , Hadeer Ahmad Elmahalawy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | معدل و أنماط العدوى الفطرية و تأثيرها على الناتج النهائي في الأطفال المصابين بسرطان الدم لميلودى الحاد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Omar Shawki Farid Arafah , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 199 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Patients with hematologic malignancies are at higher risk for invasive fungal infections (IFI) caused by molds than by yeasts, and the incidence of IFI is highest among patients with acute myeloid leukemia. Early detection and may be appropriate antifungal prophylaxis can help to decrease incidence of these infections and its related complications. Patients and methods: A double-arms retrospective and prospective study included 136 newly diagnosed Acute Myeloid Leukemia patients treated at the National Cancer Institute, Cairo university from 2011 to 2013. Prospective group (Group B) received primary Voriconazole and levofloxacin prophylaxis and compared to retrospective control regarding the infectious complications and incidence of fungal infection. Results: Median age was 5 - 6 years. Most patients were males, living in Giza and Cairo. Most patients were standard risk. Age, Gender, initial TLC, initial Monocytic Count, Risk stratifications and previous Hospitalization, were comparable between both groups. Younger age, initial free CT chest and early entry into marrow remission were associated with decreased IFI, while no effect of TLC, Monocytic count and previous Hospitalization. Voriconazole decreased IFI in prospective group significantly. Almost all primary fungal infections occurred in lungs. Most of IFI occurred during induction phase of chemotherapy. Overall survival and Event free survival were comparable between both groups. Three years OS was 38% retrospective and 36% prospective. EFS was 36.6% in pre prophylaxis group compared to 32.5% in prophylaxis group. This is due to high relapses and mortalities. Voriconazole had an accepted toxicity profile |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acute Myeloid Leukemia |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Invasive fungal infection |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Voriconazole |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hadeer Ahmad El-Mahalawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Mohamed Zaki , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lobna Mohammed Shalaby , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Aml |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Maha |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.05.Ph.D.2016.Om.I | 01010110069146000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.05.Ph.D.2016.Om.I | 01020110069146000 | 22.09.2023 | CD - Rom | 69146.CD |