Lornoxicam colon targeting solid dosage form, design, formulation and evaluation / (Record no. 56810)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02324cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031519.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160606s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.Ph.D.2016.Wa.L |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Walaa Ahmed Mohamed Eldakroury |
| 245 10 - TITLE STATEMENT | |
| Title | Lornoxicam colon targeting solid dosage form, design, formulation and evaluation / |
| Statement of responsibility, etc. | Walaa Ahmed Mohamed Eldakroury ; Supervised Mahmoud M. Ghorab , Howida Kamal Ibrahim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | إستھداف عقار اللورنوكسيكام للقولون: صياغة و تقييم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Walaa Ahmed Mohamed Eldakroury , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 185 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Non steroidal anti-inflammatory drugs (NSAIDs) got high importance as they inhibit the progression of cancer especially colon cancer. They can reduce the size of current tumor; increase the efficiency of anticancer agents and radiotherapy. However, long-term uses of non-selective NSAIDs can lead to gastrointestinal toxicity from sustained inhibition COX. Lornoxicam is a non steroidal anti-inflammatory drug of oxicam class and it has the same side effects of this group when taken orally and has a relatively short plasma half-life (3 to 4 h) which makes it a good candidate for colon targeting. It could avoid the systemic side effects, enhance its low oral bioavailability due to hepatic first pass metabolism and delay drug release to target the colon and lower the extent of colorectal carcinomas. The present study was carried out to develop oral colon targeted drug delivery systems for Lornoxicam utilizing many strategies as pH sensitive, pressure dependent, microbially triggered and time dependent enteric coating of granules, tablet and beads |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lornoxicam colon |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Solid dosage |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Targeting |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Howida Kamal Ibrahim , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Mohamed Ghorab , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.Ph.D.2016.Wa.L | 01010110069201000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.Ph.D.2016.Wa.L | 01020110069201000 | 22.09.2023 | CD - Rom | 69201.CD |