Bone metabolism and turnover markers in children with steroid-dependant \ frequently-relapsing and steroid- resistant nephrotic syndrome / (Record no. 58191)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03527cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031559.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161019s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2016.At.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Athar Marwan Abdelaliem Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Bone metabolism and turnover markers in children with steroid-dependant \ frequently-relapsing and steroid- resistant nephrotic syndrome / |
| Statement of responsibility, etc. | Athar Marwan Abdelaliem Ibrahim ; Supervised Emad Emil Ghobrial , Hanan Abdelaziz Ahmed , Riham Elsayed Hanafy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | علامات التغير فى مكونات العظام لأطفال المصابين بالمتلازمة النفروزية المعتمدة على العلاج والغير مستجيبة للعلاج - بالكورتيزون |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Athar Marwan Abdelaliem Ibrahim , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 122 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Children with nephrotic syndrome may be at risk for metabolic bone disease because of biochemical derangement caused by renal disease as well as steroid therapy. Objectives: The aim of the work was to evaluate linear growth and bone turnover markers (Calcium, Phosphorus, Alkaline phosphatase and Osteocalcin) in nephrotic syndrome patients specially SDNS{u2215}FRNS and SRNS patients in comparison to a matched control group. Methods: The study is a cross sectional case-control study that included 30 patients with SDNS{u2215}FRNS and 30 SRNS patients aged 2-15 years matched with 28 healthy control children. Both patients and controls was subjected to clinical examination and we measured serum calcium, phosphorus, alkaline phosphatase and osteocalcin). Results: Height of both SDNS{u2215}FRNS and SRNS showed lower height for age percentile compared to control group (p=0.017 and 0.00 respectively). Also height of all NS patients were negatively correlated to duration of steroid, cyclophosphamide (CYP) and cyclosporine therapy (p= 0.05, p= 0.044 and 0.02 respectively).Lower serum calcium levels were (mean 8.9±0.8) mg/dL and significant lower calcium levels in all NS patients compared to the control group (P=0.0001). Higher ALP levels in both SDNS{u2215}FRNS and SRNS patients compared to control group but with statistical significance for only SRNS patients (p= 0.02). Higher Serum osteocalcin levels in both SDNS{u2215}FRNS and SRNS patients groups compared to the control group (P=0.02 and 0.01 respectively). We also found that osteocalcin levels were negatively correlated to serum calcium levels of our patients (p-value = 0.0001). Conclusion: Glucocorticoids therapy of NS patients especially on long term treatment in SDNS{u2215}FRNS and SRNS patients affects the height of patients and some markers of bone metabolism in the form of decrease serum Calcium level and increase serum alkaline phosphatase and osteocalcin level |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Frequently-Relapsing and steroid |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Resistant nephrotic Syndrome |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Steroid-Dependant |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Emad Emil Ghobrial , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Abdelaziz Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Riham Elsayed Hanafy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samah |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2016.At.B | 01010110069961000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2016.At.B | 01020110069961000 | 22.09.2023 | CD - Rom | 69961.CD |