Pharmaceutical study on certain selective serotonin reuptake inhibitor / (Record no. 60031)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02324cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031656.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170228s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.Ph.D.2016.Sh.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shahinaze Amry Aly Fouad |
| 245 10 - TITLE STATEMENT | |
| Title | Pharmaceutical study on certain selective serotonin reuptake inhibitor / |
| Statement of responsibility, etc. | Shahinaze Amry Aly Fouad ; Supervised Saadia Ahmed Tayel , Mohamed Ahmed Elnabarawi , Emad B. Basalious |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة صيدلية لأحد مثبطات إعادة تحصيل السيروتونين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Shahinaze Amry Aly Fouad , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 200 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Dapoxetine, as dapoxetine hydrochloride (D), is the first and only selective serotonin reuptake inhibitor licensed for the treatment of PE in men. However, oral D suffers from extensive first pass metabolism, resulting in poor bioavailability (42%). Therefore, transmucosal systems of D were designed in an attempt to increase its bioavailability. In chapter (I), a 2².3¹ full factorial design was employed to study the effect of different formulation variables. An optimized formulation was prepared and evaluated. It showed a rapid permeation compared to the drug suspension. In chapter (II), nanocarrier systems for transmucosal delivery of D were prepared. In chapter (III), Part (I) and (II) involved determination of the pharmacokinetics of D after sublingual and intranasal delivery from ISTM compared to the oral market product (priligy® 30 mg, tablets) and after the intranasal delivery of D from IDNP of the optimized formulation compared to the oral D-loaded nanocarrier formulation |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Dapoxetine hydrochloride |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lyophilized matrices |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Selective serotonin reuptake inhibitor |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Emad B. Basalious , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ahmed Elnabarawi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Saadia Ahmed Tayel , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.Ph.D.2016.Sh.P | 01010110071146000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.Ph.D.2016.Sh.P | 01020110071146000 | 22.09.2023 | CD - Rom | 71146.CD |