Comparative study of different digoxin treatment regimens in Egyptian hospitals / (رقم التسجيلة. 60231)
[ عرض عادي ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03284cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031702.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170312s2016 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.M.Sc.2016.Sa.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sahar Atef Azmy Alshabasy |
| 245 10 - TITLE STATEMENT | |
| Title | Comparative study of different digoxin treatment regimens in Egyptian hospitals / |
| Statement of responsibility, etc. | Sahar Atef Azmy Alshabasy ; Supervised Samar Farid , Maggie Abbassi , Mohamed Selim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | درا{uئإآ٤}{uئإإء} {uئإؤئ}{uئإإ٤}{uئإؤ٨}{uئإ٨إ}ر{uئإإ٨}{uئإ٩٤} أ{uئإإ٨}ظ{uئإإ٤}{uئإإء} {uئإأآ}{uئإئأ}{uئإء٠}{uئإئ٤}{uئإ٩٤} {uئإإ٤}{uئإء٨}{uئإ٩٨}{uئإإ٠}{uئإؤ٤}{uئإ٩٤} {uئإؤئ}{uئإإ٠}د{uئإئ٤}{uئإء٠}و{uئإؤآ}{uئإآ٤}{uئإئ٤}ن فى ا{uئإؤئ}{uئإإ٤}{uئإآ٤}{uئإ٩٨}{uئإآ٨}{uئإؤ٤}{uئإئ٤}{uئإ٨إ}ت ا{uئإؤئ}{uئإإ٤}{uئإآأ}ر{uئإئ٤}{uئإ٩٤} |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sahar Atef Azmy Alshabasy , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 80 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Digoxin is a cardiac glycoside prescribed in heart failure and atrial fibrillation. It exerts positive inotropic, neurohormonal and electrophysiological actions on the heart. Because of inter and intra-patient variability, narrow therapeutic index, and risk of toxicity, digoxin doses are calculated based on the patient weight, renal status, indications and drug interactions. In Egypt most cardiologists give digoxin holiday (the drug is off for one or two days a week) for both atrial fibrillation and heart failure to avoid possible drug accumulation and toxicity. It is not clear if these interrupted digoxin regimens really offer safer alternative over the continuous dosing regimens without compromising the effectiveness and patient quality of life. It is anticipated that plasma digoxin levels may fall below the therapeutic range during the holiday which may affect patient clinical status. To evaluate and compare the digoxin serum concentration and patient{u2019}s quality of life in the continuous versus interrupted digoxin dosing regimens. Patients were randomized to receive one of four regimens: regimen 1: one tablet (0.25mg) daily except Friday (N=17); regimen 2: one tablet (0.25mg) daily except Thursday and Friday (N=17); regimen 3: half tablet (0.125mg) daily (N=17); and regimen 4: a tailored dose was calculated based on patient{u2019}s renal function and given daily (N=23). After reaching steady state in the two holiday regimens, two plasma samples were collected (preholiday and post holiday trough concentrations); in the other two groups one trough plasma sample was collected |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Atrial fibrillation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Digoxin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Interrupted regimens |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maggie Abbassi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Selim , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samar Farid , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.M.Sc.2016.Sa.C | 01010110071281000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.M.Sc.2016.Sa.C | 01020110071281000 | 22.09.2023 | CD - Rom | 71281.CD |