Proadrenomedullinas a prognostic biomarkerfor critically ill septic children / (Record no. 60508)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03142cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031711.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170403s2016 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2016.Sa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sally Boshra Adly |
| 245 10 - TITLE STATEMENT | |
| Title | Proadrenomedullinas a prognostic biomarkerfor critically ill septic children / |
| Statement of responsibility, etc. | Sally Boshra Adly ; Supervised Emad Emil Ghobrial , Mervat Mamdouh Ahmed Khorshied , Miriam Magdy Aziz |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دور الادرينوميدالين كأحد الدلائل الحيوية المنزرة فى الأطفال ذوى الحالات الحرجة نتيجة تسمم الدم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sally Boshra Adly , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 106 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Sepsis is among the most common causes of death in hospitals. It arises from the host response to infection. The use of new biomarkers is a promising tool to assess risk mortality among septic children in pediatric intensive care units (PICUs). Adrenomedullin (ADM), a peptide with 52 amino acids, has bactericidal activity, which is further enhanced by its regulation and modulation of complement activity. Not surprisingly, serum levels of ADM were shown to be increased in sepsis. The aim of the study was to confirm prognostic and diagnostic value of pro-adrenomedullin marker in critically ill septic children. This study was conducted on 40 patients who were admitted at pediatric intensive care unit from January 2016 to July 2016 diagnosed as sepsis in addition to 40 patients who were enrolled as control group. History taking and routine laboratory investigations were taken for cases. Serum proadrenomedullin level was measured for both cases and controls by ELISA. Our study showed that the level pro-adrenomedullin is higher in cases than controls. Its level ranged from 3.6 to 248 ng / l with mean 46.47±9.87 among studied cases while ranged from 3.8 to 9.7 ng/l with mean 5.73±0.2 in controls where there is significant statistical difference between cases and controls (p value <0.001).However, no correlation between level of pro-adrenomedullin and outcome (p value 0.720). The level of pro-adrenomedullin was higher in cases than control, thus proved that it is diagnostic of sepsis but can{u2019}t be used as prognostic factor as no correlation between its level and outcome.Future studies including larger number of patients are recommended and daily follow-up measurements are warranted to validate our results to study prognostic value of proadrenomedullin |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Biomarkers |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Proadrenomedullin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Sepsis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Emad Emil Ghobrial , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mervat Mamdouh Ahmed Khorshied , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Miriam Magdy Aziz , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2016.Sa.P | 01010110071424000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2016.Sa.P | 01020110071424000 | 22.09.2023 | CD - Rom | 71424.CD |