Effects of artocarpus heterophyllus and morus alba extracts on blood glucose, lipid profile and oxidative stress in STZ-Induced diabetic rats / (Record no. 60875)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03295cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031722.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170513s2016 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.01.M.Sc.2016.Ma.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Ali Ali Abdeen |
| 245 10 - TITLE STATEMENT | |
| Title | Effects of artocarpus heterophyllus and morus alba extracts on blood glucose, lipid profile and oxidative stress in STZ-Induced diabetic rats / |
| Statement of responsibility, etc. | Marwa Ahmed Ali Ali Abdeen ; Supervsied Samy A. Abdelazim , Mohamed T. Abdelraheem , Moustafa M. Said |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثيرات مستخلصات نباتى التوت الابيض و الجاكية على سكر و دهون الدم و الاجهاد التأكسدى فى الجرذان المصابة بمرض السكر المحدث بواسطة الستربتوزوتوسين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marwa Ahmed Ali Ali Abdeen , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 185 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In traditional medicine, morus alba (mulberry) and artocarpus heterophyllus (jackfruit) leaves extracts (MLE and JLE) were used for the treatment of diabetes mellitus. Current study was conducted to evaluate the efficacy of MLE and JLE, alone or in combination, compared to gliclazide, on streptozotocin-nicotinamide-induced diabetic rats for weeks. For both extracts, acute oral toxicity studies were carried out; total polyphenols and flavonoids were colourimetrically assayed; and different phenolic compounds and flavonoids were HPLC-assayed. Diabetes was induced in rats by a single intraperitoneal injection of streptozotocin (65 mg/kg b.w.), 15 min after the intraperitoneal injection of nicotinamide (110 mg/kg b.w.). Our observations demonstrated no signs of acute oral toxicity both extracts up to 5 g/kg b.w, beside the presence of many flavonoids and polyphenols, including hisperedin, rutin, vitexin, hisperetin, OH-Tyrosol, benzoic, chicoric and e-vanillic acids. Results also showed that diabetic rats had significant increase in fasting plasma glucose, glycated haemoglobin, all lipid profile parameters except HDL, malondialdehyde, oxide and liver tissues DNA damage levels compared to normal controls, whereas, liver glycogen, erythrocytes glutathione levels, superoxide dismutase and catalase activities were significantly decreased. Fasting plasma glucose levels and glycated haemoglobin were significantly decreased by treatment with MLE or JLE, and normalized by gliclazide. Treatment of diabetic rats with either MLE, JLE or in combination caused significant decrease of the elevated lipid profile parameters. Alterations in plasma malondialdehyde, glutathione and nitric oxide levels were reverted to near normal with MLE and combination, respectively |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Artocarpus |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gliclazide |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Morus |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed T. Abdelraheem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moustafa M. Said , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samy A. Abdelazim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.01.M.Sc.2016.Ma.E | 01010110071660000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.01.M.Sc.2016.Ma.E | 01020110071660000 | 22.09.2023 | CD - Rom | 71660.CD |