Evaluation of the effect of different immunomodulators against DT vaccine response / (Record no. 60890)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03629cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031723.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170514s2016 ua do f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.06.M.Sc.2016.Ib.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ibtehal Hesham Hafez Amin |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the effect of different immunomodulators against DT vaccine response / |
| Statement of responsibility, etc. | Ibtehal Hesham Hafez Amin ; Supervised Magdy Ali Amin , Osama Abdelwahid Hady , Amal Emad Eldin |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | درا{uئإآ٣}{uئإ٩٤} {uئإ٩٧}{uئإ٨٤}{uئإ٩آ}{uئآئئ}{uئإءإ} {uئإأآ}{uئإءء}د {uئإإ٣}{uئإإ٦} ا{uئإؤئ}{uئإإ٤}{uئإإإ}اد ا{uئإؤئ}{uئإإ٤}{uئإ٨٦}{uئإ٩آ}{uئإءإ}ة {uئإأآ}{uئإإ٠}{uئإئ٠} ا{uئإؤئ}{uئإإ٤}{uئإإ٨}{uئإ٨إ}{uئإأآ}{uئإ٩٤} {uئإأآ}{uئإإ٠}{uئإئ٠} ا{uئإآ٣}{uئإ٩٨}{uئإء٠}{uئإ٨إ}{uئإ٩١}{uئإ٩٤} {uئإؤئ}{uئإؤ٨}{uئإ٨إ}ح ا{uئإؤئ}{uئإءء}{uئإؤ٣}{uئإ٩٨}{uئآئئ}{uئإءإ}{uئآئإ}{uئإ٨إ} و ا{uئإؤئ}{uئإ٩٨}{uئآئئ}{uئإ٩٨}{uئإ٨إ}نوس |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ibtehal Hesham Hafez Amin , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 129 P. : |
| Other physical details | charts , photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Diphtheria tetanus vaccine (DT) is a biological preparation of diphtheria and tetanus toxoids that provides immunity against corynebacterium diphtheriae and clostridium tetani. Immunomodulators could modulate the immune system response. This study aimed to evaluate the effect of glucan and nigella sativa oil (NSO) as immunomodulators on diphtheria tetanus vaccine. Mice were immunized by diphtheria and tetanus vaccine. Glucan or NSO were administered at different concentrations either alone or concurrent with the DT vaccine. The concentration of tetanus antibodies, diphtheria antibodies, IL-2 and IL-4 were determined by ELISA on days 15 and 28. Complete blood pictures were also determined on day 28. The concentration of anti-Tetanus antibodies and diphtheria antibodies were significantly increased by the administration of glucan at dose of 0.5 mg (P value 0.0 and 0.001 respectively). On the other hand, administration of NSO didn't significantly affect the levels of tetanus or diphtheria antibodies. IL-4 cytokine was significantly increased by the administration of 0.1 mg or 1 mg glucan (P value 0.025 and 0.000 respectively). IL-2 cytokine significantly increased by the administration of 1 mg glucan (P value 0.047). White blood cells and red blood cells count were significantly increased by the administration of glucan (P value 0.003 and 0.033 respectively), while only PLTs count were significantly increased by NSO (P value 0.024). Concurrent administration of glucan and DT vaccine significantly increased the WBCs, RBCs and PLTs count, while concurrent administration of NSO and DT vaccine did not significantly affect WBCs, RBCs or PLTs count. This study highlights the effect of immune enhancers on improving the host immune response to DT vaccine |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DT |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Immunomodulators against |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vaccine response |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amal Emad Eldin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magdy Ali Amin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Osama Abdelwahid Hady , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.06.M.Sc.2016.Ib.E | 01010110071668000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.06.M.Sc.2016.Ib.E | 01020110071668000 | 22.09.2023 | CD - Rom | 71668.CD |