Hematopoietic stem cell transplantation in Ý-thalassemia major : (Record no. 60959)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02990cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031725.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170521s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2016.Sa.H |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Samar Sayed Ramadan Mostafa |
| 245 10 - TITLE STATEMENT | |
| Title | Hematopoietic stem cell transplantation in Ý-thalassemia major : |
| Remainder of title | The Egyptian outcome / |
| Statement of responsibility, etc. | Samar Sayed Ramadan Mostafa ; Supervised Amal Mohamed Ibrahim Elbeshlawy , Alaa Mohamed Elhaddad , Amina Abdelsalam Mahmoud |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | زرع الخلايا الجذعية فى أنيميا البحر المتوسط العظمى : |
| Remainder of title | النتائج المصرية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Samar Sayed Ramadan Mostafa , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 151 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hematopoietic stem cell transplantation (HSCT) offers curative potential for Ý-thalassemia major. To evaluate the thalassemia-free survival and outcome of stem cell transplantation in the Egyptian experience and to analyze the patients and donors{u2019} characteristics as well as transplantation related factors that could affect the graft success rate. This study retrospectively analyzed 174 patients who underwent stem cell transplantation for Ý-thalassemia major in Nasser institute, between January 1997 and December 2014. Their age at the time of transplantation ranged from 0.7 to 23.7 years; with a mean of 6.1±4.2 and median 4.6 years. One hundred and six were males (60.9%) and 68 (39.1%) females (M/F ratio: 1.6). Out of the 174 patients; 38 (21.8%) were in class I, 110 (63.2%) were in class II, and 26 (14.9%) were in class III. Twenty-six (14.9%) patients received bone marrow and 148 (85.1%) received peripheral blood stem cells (PBSC) harvest. The donors were selected based on degree of human leukocyte antigen (HLA) matching, and all of them were HLA-identical donors. 153 were matched sibling donors (MSD) and 10 were matched parent donors (MPD). The study showed that the probabilities of 5-year overall survival (OS) is 74.9%, disease free survival (DFS) is 61% and transplant related mortality (TRM) is 18.4%. Graft failure occurred in 12.6%, and the use of PBSC showing lower incidence of graft failure (GF) than BM harvest. The optimum age for transplantation is from 2-6 years, PBSC harvest and higher stem doses have more favorable outcomes and stem cell source was the main risk factor of graft failure |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | HSCT |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | OS |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thalassemia |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alaa Mohamed Elhaddad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amal Mohamed Ibrahim Elbeshlawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amina Abdelsalam Mahmoud , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2016.Sa.H | 01010110071720000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2016.Sa.H | 01020110071720000 | 22.09.2023 | CD - Rom | 71720.CD |