Assessment of the preventive effect of grape seed extract on the inflammation of tongue mucosa caused by cetuximab drug in experimental rats : (Record no. 62180)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03263cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031802.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170829s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.13.M.Sc.2016.He.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Heba Ahmed Saleh Ali |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of the preventive effect of grape seed extract on the inflammation of tongue mucosa caused by cetuximab drug in experimental rats : |
| Remainder of title | An animal study / |
| Statement of responsibility, etc. | Heba Ahmed Saleh Ali ; Supervised Dalia Hussein Elrouby , Nermine Raouf Sedhom |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم الأثر الوقائي لمستخلص بذور العنب على التهاب الغشاء المخاطى للسان الناجم عن الدواء ستوكسيماب في فئران التجارب : |
| Remainder of title | دراسة حيوانية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Heba Ahmed Saleh Ali , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 115 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | SCC is considered to be the most common type of head and neck cancer and its percentage continues to increase. Chemotherapy is considered to be the main line of treatment that is used to treat HNSCC but some patients suffer from many side effects. That{u2019}s why researchers continue their investigations to discover the chemotherapeutic drugs with the least side effects. One of the recent chemotherapeutic drugs is Cmab drug that has been approved by the United States of America. Having high affinity towards EGFR, Cmab drug directly acts against EGFR, which is usually overexpressed in invasion and metastasis of malignant tumors. OM is one of the serious side effects of Cmab drug, which may finally lead to altering the whole line of treatment by changing the drug or the dose of the drug. Inflammation of oral mucosa, especially the tongue mucosa, changes the daily functions of the patients as eating, speaking or even swallowing. GSE is one of the potent nutraceutical agents that had been studied for its anti-oxidant and anti-inflammatory effects, in addition to its antimicrobial effects and cardiovascular benefits. Its beneficial effects are attributed to the unique mix of polyphenolic compounds. Flavonoids, which are the largest groups of polyphenols, are the main components considered to be responsible for the biological properties of GSE.AntiCOX-2 is considered to be an inflammatory immunomarker that is usually not expressed in normal mucosa, but only expressed in the epithelium and connective tissue in cases of inflammation, dysplasia and cancer. GSE has anti-inflammatory and chemopreventive effects by inhibiting COX pathway and decreasing the COX-2 immunoexpression in the inflammed tissues |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Assessment of the preventive effect |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Grape seed extract |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | The inflammation of tongue mucosa caused |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalia Hussein Elrouby , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nermine Raouf Sedhom , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.13.M.Sc.2016.He.A | 01010110072511000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.13.M.Sc.2016.He.A | 01020110072511000 | 22.09.2023 | CD - Rom | 72511.CD |