Role of cyclin D1 in inflammatory bowel disease : (رقم التسجيلة. 62568)
[ عرض عادي ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03025cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031813.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170926s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.27.M.Sc.2016.Ab.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Abdulhakeem Ibrahim Abdulhakeem |
| 245 10 - TITLE STATEMENT | |
| Title | Role of cyclin D1 in inflammatory bowel disease : |
| Remainder of title | Histopathological and immunohistochemical study / |
| Statement of responsibility, etc. | Abdulhakeem Ibrahim Abdulhakeem ; Supervised Bahaa Ihab Mounir , Dina Omar Helmy , Lubna Omar Elfarouk Abdelsalam |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دور سيكلين د-1 فى مرض التهاب الأمعاء : |
| Remainder of title | دراسة نسيجية مناعية و كيميائية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Abdulhakeem Ibrahim Abdulhakeem , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 119 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Inflammatory bowel disease (IBD) is one of the important causes of chronic diarrhea that shows an increasing incidence in the world especially in the middle east. Cell cycle progression is facilitated by CDKs that are activated by cyclins, including cyclin D1. Evidence of the involvement of cyclin gene alterations and overexpression in human cancer is growing. Aim of Work: This work aimed to examine immunohistochemical (I.H.C.) expression of cyclin D1 in inflammatory bowel disease and its correlation with the age, sex, disease activity, dysplasia and clinical presentation of the disease as we try to find a relation between the cyclin D1 expression on one hand with the disease activity and dysplasia in the other hand. Methods: This study consisted of 40 cases of IBD; 35 cases were ulcerative colitis and 5 cases were crohn{u2019}s disease retrieved as routinely processed paraffin blocks taken from the department of pathology, Kasr Elainy hospital in addition to some private labs. For all specimens, the clinical data were available on the computer files including age and sex of the patients as well as their clinical presentation. Microscopic examination of the H and E stained slides was done to assess the degree of disease activity (and dysplasia if present) for each slide. The activity of IBD was assessed depending on degree of inflammation, percentage of cryptitis, erosions and ulcerations. I.H.C. reactions were carried out by using cyclin D1 monoclonal antibody. Immunohistochemical expression of cyclin D1 was estimated by evaluating the intensity of brown nuclear staining of intestinal epithelial cells |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CDKs |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cyclin D1 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Inflammatory bowel disease |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bahaa Ihab Mounir , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Omar Helmy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lubna Omar Elfarouk Abdelsalam , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.27.M.Sc.2016.Ab.R | 01010110072784000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.27.M.Sc.2016.Ab.R | 01020110072784000 | 22.09.2023 | CD - Rom | 72784.CD |