Synthesis and biological studies of new heterocyclic compounds containing pyrazole, thiazole and/or thiadiazole moieties / (Record no. 62821)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03355cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031822.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171009s2016 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.10.M.Sc.2016.Em.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Kamal Mousa Dewidar |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis and biological studies of new heterocyclic compounds containing pyrazole, thiazole and/or thiadiazole moieties / |
| Statement of responsibility, etc. | Eman Kamal Mousa Dewidar ; Supervised Sobhy Mohamed Gomaa |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | {uFE97}{uFEA4}{uFEC0}{uFBFF}{uFEAE} و درا{uئإآ٣}{uئإ٩٤} ا{uئإؤئ}{uئإإ٨}{uئإآ٨}{uئإ٨إ}ط ا{uئإؤئ}{uئإ٩٢}{uئآئئ}{uئإإإ}{uئإؤئ}{uئإإإ}{uئإ٩ئ}{uئإئ٠} {uئإؤئ}{uئإإ٤}{uئإءإ}{uئإؤآ}{uئإ٩٢}{uئإ٨إ}ت {uئإأئ}{uئآئئ}{uئإءإ} {uئإإ٣}{uئإ٩٨}{uئإء٠}{uئإ٨إ}{uئإإ٧}{uئإآ٤}{uئإ٩٤} ا{uئإؤئ}{uئإء٤}{uئإإ٠}{uئإؤ٨}{uئإ٩٤} ا{uئإؤئ}{uئإ٩٨}{uئإئ٠} {uئإ٩٧}{uئإء٤}{uئإ٩٨}{uئإإإ}ى {uئإأآ}{uئإإ٠}{uئإئ٠} {uئإإ٣}{uئإآ٨}{uئإ٩٨}{uئإؤ٨}{uئإ٨إ}ت {uئإء٣}{uئإإ٠}{uئإؤ٨}{uئإ٨إ}ت {uئإ٩١}{uئآئئ}{uئإءإ}ازول: {uئإ٩آ}{uئآئئ}{uئإ٨إ}زول و/ او-{uئإ٩آ}{uئآئئ}{uئإ٨إ}دا{uئآئإ}{uئإ٨إ}زول |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Kamal Mousa Dewidar , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 197 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The original work of the submitted thesis consists of two research projects: In the first part: A new series of 7-arylazopyrazolo[5,1-c][1,2,4] triazoles was synthesized via reaction of 3-amino-4-(arylhydrazono)-4,5-dihydropyrazol-5-one with hydrazonoyl halides using triethylamine as a basic catalyst. The structure of all the synthesized compounds was confirmed on the basis of elemental and spectral analyses data. Moreover, the antimicrobial and antitumor activities of these compounds were evaluated and the results obtained indicate the weak efficacy of some of them as antibacterial agents. But, the results of antitumor activity against HepG-2 liver cancer and HCT-116 colon cancer of some derivatives showed good activity in comparison with the reference drugs. In the second part: A novel series of 5-arylazothiazoles was prepared from 2-(-1-morpholino-1-(2-arylhydrazono)propan-2-ylidene)-hydrazinecarbothioamide by different methods. The structures of the newly synthesized compounds were established on the basis of spectroscopic evidences and their synthesis by alternative methods. Moreover, the newly synthesized products were evaluated for their anti-cancer activities and the results show that some derivatives have good to mild utility as antitumor operators. Moreover, the computational studies using MOE 2014.09 software are confirming the results of biological activity |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | New heterocyclic compounds containing pyrazole |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thiadiazole moieties |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thiazole |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sobhy Mohamed Gomaa , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.10.M.Sc.2016.Em.S | 01010110073038000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.10.M.Sc.2016.Em.S | 01020110073038000 | 22.09.2023 | CD - Rom | 73038.CD |