Surveillance biopsy and effect of different immunosuppression regimen on graft pathology in pediatric renal transplantation / (رقم التسجيلة. 63686)
[ عرض عادي ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03229cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031847.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171126s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.Ph.D.2017.Mo.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ahmed Abdelmawla Ahmed |
| 245 10 - TITLE STATEMENT | |
| Title | Surveillance biopsy and effect of different immunosuppression regimen on graft pathology in pediatric renal transplantation / |
| Statement of responsibility, etc. | Mohamed Ahmed Abdelmawla Ahmed ; Supervised Fatina Ibrahim Fadel , Abeer Mohamed NourEldin , Wesam Ismail Moustafa |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | خزعه المراقبه و أثر الأدويه المختلفه المثبطه للمناعه على نسيج الكلي فى زرع الكلى فى الأطفال |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mohamed Ahmed Abdelmawla Ahmed , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 132 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Early graft monitoring has the potential to extend the renal graft survival in pediatric recipients. By the time that clinical diagnosis is confirmed histologically, renal scarring may be too advanced to make delayed treatment a realistic option. Surveillance biopsy has been useful in detection of subclinical immunological as well as non- immunological graft injury.The aim of the study is to study the pathological graft data one month post transplantation by surveillance biopsy and to evaluate the histopathological impact of different immunosuppression protocols on the graft four months post transplantation. Methods: This is a prospective interventional cohort study that included 20 living donor renal transplant recipients being followed up at kidney transplantation outpatient clinic, Cairo university children`s Hospital (Abo Elreesh).All cases received the classic triple maintenance immunosuppression protocol (CNI, steroids and MMF) for one month then cases were subdivided into two groups based on their maintenance immunosuppression therapy furthermore: group (A) (12 cases) continued on CNI based triple therapy protocol, group (B) (8 cases) shifted to m-TOR inhibitors low dose CNI protocol. Surveillance biopsies were done for all cases at one and four month post-transplantation. Results: One month surveillance biopsies were totally normal in 9 (45%) cases. Acute CNI toxicity was found in 5 (25%) cases. Subclinical rejection (SCR) was found in 4 (20%) cases (Acute SCR in 2 cases and borderline subclinical changes in 2 cases). Four month surveillance biopsy revealed 6 (30%) cases with SCR 5 cases with acute SCR of the evirolimus based immunosuppression and 1 case with borderline subclinical changes of the classic triple therapy |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Evirolimus |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Subclinical rejection |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Surveillance biopsy |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abeer Mohamed NourEldi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fatina Ibrahim Fade , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wesam Ismail Moustafa , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.Ph.D.2017.Mo.S | 01010110073596000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.Ph.D.2017.Mo.S | 01020110073596000 | 22.09.2023 | CD - Rom | 73596.CD |