Prognostic value of estimated plasma fibrinogen level in comparison to measured fibrinogen level in traumatized critically Ill patients / (Record no. 64070)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03637cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031859.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171217s2017 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.09.M.Sc.2017.Wa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Walaa Mohamed Zaki Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Prognostic value of estimated plasma fibrinogen level in comparison to measured fibrinogen level in traumatized critically Ill patients / |
| Statement of responsibility, etc. | Walaa Mohamed Zaki Mohamed ; Supervised Emad Eldein Omar Abdalaziz , Mervat Mohamed Khalaf , Enas Abdalatif Ahmed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | القيمة التنبؤية للمستوى التقديرى للفيبرينوجين فى البلازما مقارنة بمستواة المقاس فى البلازما فى مرضى الاصابات الحرجة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Walaa Mohamed Zaki Mohamed , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 185 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Critical Care Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Fibrinogen plays an important role in hemostasis and is the first coagulation factor to reach critical levels in massively bleeding trauma patients. rapid estimation of plasma fibrinogen (FIB) is essential upon emergency room (ER) admission, but is not part of routine coagulation monitoring in many centers. We investigated the predictive ability of the laboratory parameters hemoglobin (Hb) and base excess (BE) upon admission, as well as the Injury Severity Score (ISS), to estimate FIB in major trauma patients.also to predict mortality and morbidity in relation to these factors. Methods: In this prospective observational study, major trauma patients with documented FIB analysis upon ER admission were eligible for inclusion. FIB was correlated with Hb, BE and ISS, alone and in combination, using regression analysis. Results: A total of 80 critically ill trauma patients and 20 case control group were enrolled. FIB upon admission correlated strongly with Hb, BE and ISS. Multiple regression analysis showed that Hb , BE and ISS predicted FIB . using this equation model Estimated log Fibrinogen = 3.188+0.243HB - 0.019HB2 + 0.019BE - 0.05 ISS +0.0002 ISS2 we also predicted Cut off value for fibrinogen to predict survival: Fibrinogen level at 222.5 was predictive for survival with AUC, with sensitivity of 67.3% and specificity of 78% as p value was 0.0001. ISS group (5) had shown a significant higher frequency of all types of complications. By comparing the 3 ISS groups for age, hemodynamic, laboratory variables Critical group (ISS5) had a significantly lower SBP, PH, Hb, GCS and higher HR, RR, BE, INR, APACHE II and length of stay Conclusions: Upon ER admission, FIB of major trauma patients shows strong correlation with rapidly obtainable, routine laboratory parameters such as Hb and BE. These two parameters might provide an insightful and rapid tool to identify major trauma patients at risk of acquired hypofibrinogenemia. Early calculation of ISS could further increase the ability to predict FIB in these patients. We propose that FIB can be estimated during the initial phase of trauma care based on bedside tests |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DIC |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TIC |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Trauma |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Emad Eldein Omar Abdalaziz , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Enas Abdalatif Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mervat Mohamed Khalaf , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.09.M.Sc.2017.Wa.P | 01010110073841000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.09.M.Sc.2017.Wa.P | 01020110073841000 | 22.09.2023 | CD - Rom | 73841.CD |