Design and synthesis of new quinoline derivatives as potential inhibitors of tumor necrosis factor / (Record no. 66999)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02330cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032029.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180808s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.04.M.Sc.2017.Na.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nahla Said Mohamed Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Design and synthesis of new quinoline derivatives as potential inhibitors of tumor necrosis factor / |
| Statement of responsibility, etc. | Nahla Said Mohamed Ibrahim ; Supervised Afaf K. Elansary , Hanan Hassan Kadry , Lamia Wagdy Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تصميم و تشييد مشتقات كينولين جديدة كمثبطات محتملة للعامل المثبط للورم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Nahla Said Mohamed Ibrahim , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 107 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This thesis consists of six chapters. The first chapter is an introduction about tumor necrosis factor-Ü and its inhibitors followed by the chemistry of quinolones and different methods of their synthesis. The second chapter shows the objectives of the work and the Schemes designed for the preparation of the target compounds. The third chapter consists of the theoretical discussion of the experimental work. The fourth chapter studies the experimental part of the thesis which contains the detailed procedures used for the synthesis of the target compounds and intermediates, in addition to the physical properties, elemental analysis and spectral data of the synthesized compounds. The fifth chapter is the biological evaluation of the final compounds which includes the evaluation of their TNF-Ü inhibitory activity and anticancer evaluation. The final and sixth chapter is the docking study of final compounds on tumor necrosis factor converting enzyme |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antitumor |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Quinolone |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Tumor necrosis factor |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Afaf Kamal Eldin Elansary , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Hassan Kadry , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lamia Wagdy Mohamed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.04.M.Sc.2017.Na.D | 01010110075497000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.04.M.Sc.2017.Na.D | 01020110075497000 | 22.09.2023 | CD - Rom | 75497.CD |