Effect of calcium disodium EDTA nanoparticles against cadmium toxicity in Rats / (Record no. 68342)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03003cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032111.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 181104s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.07.Ph.D.2018.Sa.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Safa Mohamed Saleh Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of calcium disodium EDTA nanoparticles against cadmium toxicity in Rats / |
| Statement of responsibility, etc. | Safa Mohamed Saleh Ibrahim ; Supervised Eiman M. Elsaied , Osama S. Eltawil , Manal B. Mahmoud |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير جزيئات الكالسيوم ثنائى الصوديوم اديتات متناهية الصغر ضد التسمم بالكادميوم فى الفئران |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Safa Mohamed Saleh Ibrahim , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 141 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Forensic Medicine and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In this study, the median lethal dose (LD50) of cadmium sulfate was determined firstly. Then, the animals were classified at the start of the experiment, into two groups; a control (contains 15 rats) and an intoxicated one (contains 45 rats), which received drinking water contains 30 ppm cadmium for 10 weeks. At the end of the 6th week of the experiment, the intoxicated group was subdivided equally into three groups. The second and third groups respectively were injected intraperitoneally with 50 mg/kg/day macroparticles or nanoparticles CaNa₂EDTA for 4 courses (4 days each) with an interval of 3 days between the courses. Results showed that, the estimated median lethal dose (LD50) of cadmium sulfate for adult female rats was 240 mg/kg. Cadmium significantly reduced body weight gain and food consumption and induced a marked depression. Cadmium also induced histopathological changes in liver, kidney and bones and decreased bone mineralization as revealed by X-ray examination. Serum urea and creatinine concentrations were significantly increased by cadmium. Concentrations of cadmium and metallothionein in serum and urine were significantly increased in cadmium-intoxicated rats. Cellular immune response (as determined by the total and differential leucocytic counts, the phagocytic activity of neutrophils, lymphocytes transformation and serum lysozyme activity) were significantly affected. Humoral immune response as estimated by the measurement of electrophoresis pattern of serum proteins and cytokines production (serum IL-2 and IL-6) was significantly decreased by cadmium |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cadmium |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CaNa₂EDTA |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nanoparticles |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eiman Mostafa Elsaied , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Manal Bahaa Eldin Mahmoud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Osama Samir Eltawil , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.07.Ph.D.2018.Sa.E | 01010110076339000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.07.Ph.D.2018.Sa.E | 01020110076339000 | 22.09.2023 | CD - Rom | 76339.CD |