Synthesis of new pyrazoles as anti-inflammatory agents / (Record no. 70343)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02746cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032211.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190219s2018 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.04.M.Sc.2018.Sh.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shimaa Magdy Ibrahim Alhamaky |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis of new pyrazoles as anti-inflammatory agents / |
| Statement of responsibility, etc. | Shimaa Magdy Ibrahim Alhamaky ; Supervised Mohamed A. Shaaban , Ashraf F. Zaher , Lamia W. Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تشييد مشتقات بيرازول جديدة كعوامل مضادة للالتهاب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Shimaa Magdy Ibrahim Alhamaky , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 97 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This thesis includes four chapters in addition to references and arabic summary. The first chapter is the introduction, which consist of a brief literature survey of the synthesis and reactions of pyrazoles. It also involve an account on the anti-inflammatory agents. The second chapter involves the objectives of this work based on structure activity relationship and molecular modelling study. It also demonstrates the schemes of synthesis of the new derivatives. The third chapter clarifies the theoretical discussion of the experimental work used to synthesis in addition to spectroscopic data of the starting materials I , II and the target new compounds IIIa-f, IVa-L, Va-f. The fourth chapter is divided in to three parts representing the experimental part of the thesis. The first part is the synthetic approach that comprises the detailed methods for preparation of designed compounds in three schemes. Scheme I : includes synthesis of I followed by reaction with o-fluoro aniline affording derivative II. This was followed by coupling with diazotized aromatic amines in ethanol in presence of sodium acetate to afford IIIa-f. Scheme II : involves the mannich procedure for the reaction of IIIa-f with anilin or 2,6-dimethyl aniline and 40% formaldehyde in ethanol at 60 oC to afford IVa-L. Scheme III: involves the synthesis of Va-f by cyclization reaction of II with appropriate aromatic aldehydes and malononitrl in ethanol containing ammonium acetate |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mannich reaction |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pyrazoles |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pyrazolopyridine |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ashraf Fouad Zaher , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lamia Wagdy Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Abdelrahman Shaaban , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.04.M.Sc.2018.Sh.S | 01010110077242000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.04.M.Sc.2018.Sh.S | 01020110077242000 | 22.09.2023 | CD - Rom | 77242.CD |