Gene expression of vanin-1 (VNN-1) in Egyptian adults with immune thrombocytopenia ITP / (Record no. 70659)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02767cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032221.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190305s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.18.M.Sc.2018.Na.G |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nashwa Mohamed Nor Eldin AboElsoad |
| 245 10 - TITLE STATEMENT | |
| Title | Gene expression of vanin-1 (VNN-1) in Egyptian adults with immune thrombocytopenia ITP / |
| Statement of responsibility, etc. | Nashwa Mohamed Nor Eldin AboElsoad ; Supervised Alia Abdelaziz Ayad , Doaa Mohamed Eldemerdash , Rania Elsayed Hussein |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقدير مستوى جين الفانين 1 فى المرضى البالغين المصريين الذين يعانون من مرض نقص الصفائح الدموية المناعى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Nashwa Mohamed Nor Eldin AboElsoad , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 105 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Distinguishing self-limited acute ITP from chronic ITP identify potential targets for therapeutic interventions in the group at risk for chronic ITP. Overproduction free radical in the absence of adequate antioxidant defense may cause irreversible changes to biomolecules and the generation of neo-antigenic determinants. This may ultimately contribute to epitope spreading and the abrogation of self-tolerance. Vanin-1 (VNN1) has been proven to be an oxidative stress sensor, which regulates endogenous glutathione levels. Objectives: to find an association between overexpressed VNN1 in blood and progression to chronic ITP. Method: The study was carried out on 40 cases and 10 healthy controls patients were grouped into: Group A: 30 patients with acute ITP Group B: 10 patients with chronic ITP. All patients were subjected to Vanin1 gene level by PCR technique. Results: Vanin1 gene was higher in patients with ITP than control with statistically significant values, (P-value< 0.001) vanin1 gene was higher in acute than chronic patients but the difference was statistically insignificant, (P value >0.05) .correlation between vanin1 gene and hemoglobin, leucocytic count and platelet count before treatment in group B (chronic ITP)and groups A (responder and non-responders) were statistically insignificant |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Egyptian adults |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ITP |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vanin1 gene |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alia Abdelaziz Ayad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mohamed Eldemerdash , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania Elsayed Hussein , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.18.M.Sc.2018.Na.G | 01010110077333000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.18.M.Sc.2018.Na.G | 01020110077333000 | 22.09.2023 | CD - Rom | 77333.CD |