Estimation of level of erap1 expression in lesional and non lesional skin of psoriatic patients and healthy controls / (Record no. 71808)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02904cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032255.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190505s2018 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2018.Do.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mostafa Kamel Ahmed |
| 245 10 - TITLE STATEMENT | |
| Title | Estimation of level of erap1 expression in lesional and non lesional skin of psoriatic patients and healthy controls / |
| Statement of responsibility, etc. | Doaa Mostafa Kamel Ahmed ; Supervised Dina Metwally Salama , Rana Fathy Hilal , Amul Mohamed Abdelrahim Badr |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم مستوى انزيم الشبكة الأندوبلازمية أمينوببتيداز1 فى الجلد لمرضى الصدفية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Doaa Mostafa Kamel Ahmed , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 132 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venereology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Psoriasis is a chronic, inflammatory autoimmune disease of the skin, characterized by keratinocyte hyper proliferation and resulting in erythematous, scaly plaques. The association of enzymes involved in the final processing of MHC-I ligands with inflammatory diseases was reported and the association of ERAP1 in psoriasis was reported. Objectives: Estimation of level of ERAP1 expression in lesional and non lesional skin of psoriatic patients and healthy controls and its role in pathegenesis of psoriasis. Patients and methods: Twenty-five psoriatic patients and thirty healthy controls were enrolled in this study. All patients were subjected to detailed history and clinical examination to determine severity (PASI score) of psoriasis. Skin biopsies were obtained from all subjects, one from lesional and other from non lesional skin of psoriatic patients and one from the healthy controls. ERAP1 level was measured using PCR technique. Results: Results revealed a higher level of expression of ERAP1 between psoriatic patients and controls regarding tissue lesional and non- lesional ERAP1 level (p values<0.001). Positive corrrelation was detected between psoriatic patients and healthy controls regarding tissue ERAP1 level. In addition, there was statistically significant difference between lesional ERAP1, non-lesional ERAP1 and PASI score (p value<0.001) and positive correlation between lesional and non-lesional ERAP1 level in psoriatic patients and PASI score |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antigen processing |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Psoriasis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Tissue lesional ERAP1 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amul Mohamed Abdelrahim Badr , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Metwally Salama , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rana Fathy Hilal , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2018.Do.E | 01010110077865000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2018.Do.E | 01020110077865000 | 22.09.2023 | CD - Rom | 77865.CD |