Development and validation of quantitative structure{u2013}retention relationship models for some antibacterial agents in liquid chromatography / (Record no. 72387)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02699cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032314.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190613s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.02.Ph.D.2018.En.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Enas Hamid Mohammed Tolba |
| 245 10 - TITLE STATEMENT | |
| Title | Development and validation of quantitative structure{u2013}retention relationship models for some antibacterial agents in liquid chromatography / |
| Statement of responsibility, etc. | Enas Hamid Mohammed Tolba ; Supervised Marwa Ahmed Fouad , Manal Abdelhamid Elshal , Ahmed Mahmoud Elkerdawy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التطوير والتحقق من نماذج العلاقة الكمية بين التركيب الكيميائي والاحتباس لبعض مضادات البكتيريا في كروماتوجرافيا السائل |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Enas Hamid Mohammed Tolba , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 163 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In this thesis, antibacterial agents were assessed regarding their chromatographic behavior in order to build reliable QSRR models. Such models facilitate the analysis of this class of pharmaceutical compounds in their pharmaceutical, biological and environmental applications. The studied class was divided into three groups: Ý-lactam antibiotics, quinolones and sulfonamides. For Ý-lactam antibiotics, two validated QSRR models were built in order to predict the retention factors of several Ý-lactams. These models are: firefly algorithm and forward selection multiple linear regression models.Then, statistical analysis methods were conducted to compare between the two models. For quinolones, we planned to relate their retention behavior with their different ionization state through QSRR model based on advanced firefly algorithm and support vector learning machine. For sulfonamides, the point of view was to study the effect of using different ratios of organic modifier (acetonitrile) on their retention behavior through building validated QSRR model using advanced firefly as a variable selection algorithm and support vector as a modeling machine |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Quantitative structure retention relationship |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Quinolones |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ý-lactams |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mahmoud Elkerdawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Manal Abdelhamid Elshal , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Fouad |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.02.Ph.D.2018.En.D | 01010110078413000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.02.Ph.D.2018.En.D | 01020110078413000 | 22.09.2023 | CD - Rom | 78413.CD |