Evaluation of hepatocyte-derived microRNA-122(miR-122) For diagnosis of selected hepatobiliary diseases of dogs / (Record no. 73252)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02854cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032339.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190804s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.09.Ph.D.2019.Em.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Shawky Ramadan Mahmoud |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of hepatocyte-derived microRNA-122(miR-122) For diagnosis of selected hepatobiliary diseases of dogs / |
| Statement of responsibility, etc. | Eman Shawky Ramadan Mahmoud ; Supervised Taher A. Baraka , Faisal A. Torad , Shaymaa I. Salem |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم ميكرو ار ان ايه-122(ام اي ار -122) المستمد من الخلايا الكبدية لتشخيص أمراض الكبد والمراره المختاره في الكلاب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Shawky Ramadan Mahmoud , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 125 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Internal Medicine and Infectious Diseases |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hepatobiliary diseases are commonly encountered in canine medicine and can be classified into parenchymal, vascular, biliary or neoplastic diseases. Diagnosis of liver diseases is considered a chal»lenge for a veterinarian and requires a lot of diagnostic workup as specific clinical signs become overt only when hepatocellular damage became massive so new sensitive, non invasive hepatic diagnostic biomarkers are needed. In this study 64 dogs were used, 15 of them were used as a normal control group, 10 of them were used for induction of steroid hepatopathy and 39 of them suffered from hepatobiliary diseases. Diagnostic workup were recorded including clinical examination, hematology, serum biochemical constituents, abdominal ultrasonography, US guided fine-needle liver biopsy for cytological and histopathological investigations and serum hepatocyte derived miRNA-122 analyzed by real-time quantitative polymerase chain reaction. In conclusion, serum hepatocyte derived miRNA-122 is of diagnostic value and highly stable, non invasive, easily measurable blood indicator for detection of hepatocellular injury in dogs in addition to miRNA-122 highly significant elevated in acute hepatitis, chronic hepatitis, canine multicentric lymphoma involving liver, slightly elevated in steroid induced hepatopathy and moderate elevated in biliary diseases |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Canine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hemato-biochemical analysis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatobiliary diseases |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faisal A. Torad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shaymaa I. Salem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Taher A. Baraka , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.09.Ph.D.2019.Em.E | 01010110078870000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.09.Ph.D.2019.Em.E | 01020110078870000 | 22.09.2023 | CD - Rom | 78870.CD |