Investigation of resistance mechanisms in colistin resistant some enterobacteriaceae in cancer patients in Egypt / (Record no. 73459)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02680cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032345.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190822s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.06.M.Sc.2019.As.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Asmaa Abdulhak Elsayed Mohammed Abdelaal |
| 245 10 - TITLE STATEMENT | |
| Title | Investigation of resistance mechanisms in colistin resistant some enterobacteriaceae in cancer patients in Egypt / |
| Statement of responsibility, etc. | Asmaa Abdulhak Elsayed Mohammed Abdelaal ; Supervised Magdy Aly Amin , Hadeer Elmahallawy , Mai Mahmoud Zafer |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التحقيق في آليات مقاومة الكوليستين في البكتيريا المعوية لدى مرضى السرطان في مصر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Asmaa Abdulhak Elsayed Mohammed Abdelaal , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 93 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The recent emergence of plasmid-encoded colistin resistance mechanism (MCR-1and MCR-2) among human enterobacterial isolates presents a threat for the rapid global spread. Colistin resistance is mainly mediated by the alteration in the LPS of bacterial outer membrane; these alterations are mediated by mutations in mgrB gene which is the most commonly reported. This study aimed to investigate the colistin-resistance rates among Klebsiella pneumoniae and Escherichia coli isolates obtained from Cancer patients in Egypt and the possible underlying mechanisms of colistin resistance. Minimum inhibitory concentrations (MICs) to colistin were determined according to the (EUCAST) guidelines. Broth microdilution and and E-tests were used to test colistin susceptibility. PCR and sequencing of mcr-1 and mcr-2 were performed. The mgrB gene was amplified and sequenced. Clonal diversity for colistin resistant K. pneumoniae isolates was evaluated by multilocus sequence typing (MLST). Four hundred and fifty Enterobacteriaceae were included in this study. Forty (8.8%) colistin-resistant isolates including 22 K. pneumoniae and 18 E. coli were detected over 10 months. Fifty % of the colistin resistant isolates were carbapenem resistant (20/40) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cancer patients |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Colistin resistant |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Enterobacteriaceae |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hadeer Elmahallawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magdy Aly Amin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mai Mahmoud Zafer , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Asmaa |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.06.M.Sc.2019.As.I | 01010110078916000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.06.M.Sc.2019.As.I | 01020110078916000 | 22.09.2023 | CD - Rom | 78916.CD |