Impact of dendritic cells and natural killer cells cytokines on hepatitis C viral infection in Egyptian patients / (Record no. 74080)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02852cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032404.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190923s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.21.M.Sc.2019.Sh.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shimaa Rabah Abdelmo{u2019}ez Taha |
| 245 10 - TITLE STATEMENT | |
| Title | Impact of dendritic cells and natural killer cells cytokines on hepatitis C viral infection in Egyptian patients / |
| Statement of responsibility, etc. | Shimaa Rabah Abdelmo{u2019}ez Taha ; Supervised Somaya Osman Eldeeb , Abdelrahman Zekri , Maysa Elrazky |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير سيتوكينات الخلايا المتشعبة والخلايا القاتلة الطبيعية على الإصابة بالإلتهاب الكبدى الفيروسى سى فى المرضى المصريين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Shimaa Rabah Abdelmo{u2019}ez Taha , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 112 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | helper (Th) cytokines play a key role in the immunological aspects of hepatitis C virus (HCV) pathogenesis. The pattern of Th1 (IL-2, interferon (IFN)-Þ), Th2 (IL-10), and immunomodulatory cytokines (IL-12, IL-1Ý, IFN-Ü and tumor necrosis factor-Ü receptor (TNF-ÜR2) balance participated in the outcome of host immune responses. The study aimed to investigate the serum levels of Th1/Th2 and immunomodulatory cytokines in HCV infected patients in both sexes during various liver disease stages compared to healthy controls. Blood samples were collected from 16 healthy individuals and 77 patients at different disease stages including chronic, cirrhosis, and hepatocellular carcinoma (HCC). Serum cytokine levels were measured by ELISA. Levels of serum IL-12 and IL-10 were significantly higher in both sexes in all groups than those in corresponding healthy subjects. Whereas, HCV infected female patients showed significant lower levels of IL-2, IL-1Ý, IFN-Ü in chronic and cirrhosis stages than corresponding males. Serum level of IFN-Þ could be utilized as biomarker for early detection of HCC. Finally, cytokine response variation in sex during various stages of disease, imply that the subsequent activation and attenuated functional immune responses displayed differences in the balance of Th1 and immunomodulatory related cytokines between females and males upon infection |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cirrhosis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cytokines |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gender |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdelrahman Zekri , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maysa Elrazky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Somaya Osman Eldeeb , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.21.M.Sc.2019.Sh.I | 01010110079390000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.21.M.Sc.2019.Sh.I | 01020110079390000 | 22.09.2023 | CD - Rom | 79390.CD |